Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.130
Description:Pyrrole-2-carboxylate monooxygenase.
Alternative Name: Pyrrole-2-carboxylate oxygenase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.130
BRENDA Enzyme Link: BRENDA 1.14.13.130
KEGG Enzyme Link: KEGG1.14.13.130
BioCyc Enzyme Link: BioCyc 1.14.13.130
ExPASy Enzyme Link: ExPASy1.14.13.130
EC2PDB Enzyme Link: EC2PDB 1.14.13.130
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.130
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.130
IntEnz Enzyme Link: IntEnz 1.14.13.130
MEDLINE Enzyme Link: MEDLINE 1.14.13.130
MSA:

1.14.13.130;

Phylogenetic Tree:

1.14.13.130;

Uniprot:
M-CSA:
RHEA:30351 H(+) + NADH + O2 + pyrrole-2-carboxylate = 5-hydroxypyrrole-2-carboxylate + H2O + NAD(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Two-component flavin-dependent pyrrole-2-carboxylate monooxygenase from Rhodococcus sp.Becker D, Schräder T, Andreesen JR1997 Nov 19395321
Purification and characterization of a pyrrole-2-carboxylate oxygenase from Arthrobacter strain Py1.Hormann K, Andreesen JR1994 Mar8011178