EC number:1.14.13.146

Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.146
Description:Taxoid 14-beta-hydroxylase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.146
BRENDA Enzyme Link: BRENDA 1.14.13.146
KEGG Enzyme Link: KEGG1.14.13.146
BioCyc Enzyme Link: BioCyc 1.14.13.146
ExPASy Enzyme Link: ExPASy1.14.13.146
EC2PDB Enzyme Link: EC2PDB 1.14.13.146
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.146
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.146
IntEnz Enzyme Link: IntEnz 1.14.13.146
MEDLINE Enzyme Link: MEDLINE 1.14.13.146

EC number:1.14.13.146

MSA:

1.14.13.146;
Phylogenetic Tree:

1.14.13.146;
Uniprot:
M-CSA:
RHEA:31971 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(+) + NADPH + O2 = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + H2O + NADP(+)
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH2;+0:9]-[CH;+0:10]=[CH;+0:11]-1.[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:13].[*:4]-[n+;H0:5]1:[cH;+0:6]:[c;H0;+0:7](-[*:8]):[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:1.[OH2;+0:14]
Reaction
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References

TitleAuthorsDatePubMed ID
Taxoid metabolism: Taxoid 14beta-hydroxylase is a cytochrome P450-dependent monooxygenase.Jennewein S, Rithner CD, Williams RM, Croteau R2003 May 1512729625