EC number:1.14.13.16

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.16
Description:Cyclopentanone monooxygenase.
Alternative Name: Cyclopentanone 1,2-monooxygenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.16
BRENDA Enzyme Link: BRENDA 1.14.13.16
KEGG Enzyme Link: KEGG1.14.13.16
BioCyc Enzyme Link: BioCyc 1.14.13.16
ExPASy Enzyme Link: ExPASy1.14.13.16
EC2PDB Enzyme Link: EC2PDB 1.14.13.16
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.16
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.16
IntEnz Enzyme Link: IntEnz 1.14.13.16
MEDLINE Enzyme Link: MEDLINE 1.14.13.16

EC number:1.14.13.16

MSA:

1.14.13.16;
Phylogenetic Tree:

1.14.13.16;
Uniprot:
M-CSA:
RHEA:15737 cyclopentanone + H(+) + NADPH + O2 = 5-valerolactone + H2O + NADP(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[CH2;+0:12]-[*:13].[H+;H0:14].[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]=[C;H0;+0:10](-[*:11])-[O;H0;+0:15]-[CH2;+0:12]-[*:13].[OH2;+0:16]
Reaction
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References

TitleAuthorsDatePubMed ID
Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans.Fiorentini F, Geier M, Binda C, Winkler M, Faber K, Hall M, Mattevi A2016 Apr 1526771671
Broadening the scope of Baeyer-Villiger monooxygenase activities toward α,β-unsaturated ketones: a promising route to chiral enol-lactones and ene-lactones.Reignier T, de Berardinis V, Petit JL, Mariage A, Hamzé K, Duquesne K, Alphand V2014 Jul 2524903773
Cloning and characterization of a gene cluster involved in cyclopentanol metabolism in Comamonas sp. strain NCIMB 9872 and biotransformations effected by Escherichia coli-expressed cyclopentanone 1,2-monooxygenase.Iwaki H, Hasegawa Y, Wang S, Kayser MM, Lau PC2002 Nov12406764