EC Tree |
1. Oxidoreductases |
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
ID: | 1.14.13.171 |
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Description: | Neopentalenolactone D synthase. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.14.13.171 |
BRENDA Enzyme Link: | BRENDA 1.14.13.171 |
KEGG Enzyme Link: | KEGG1.14.13.171 |
BioCyc Enzyme Link: | BioCyc 1.14.13.171 |
ExPASy Enzyme Link: | ExPASy1.14.13.171 |
EC2PDB Enzyme Link: | EC2PDB 1.14.13.171 |
ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.171 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.171 |
IntEnz Enzyme Link: | IntEnz 1.14.13.171 |
MEDLINE Enzyme Link: | MEDLINE 1.14.13.171 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:34639 | 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 = H2O + NADP(+) + neopentalenolactone D |
RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[C;H0;+0:4](=[*:5])-[*:6].[*:7]-[N;H0;+0:8]1-[CH;+0:9]=[C;H0;+0:10](-[*:11])-[CH2;+0:12]-[CH;+0:13]=[CH;+0:14]-1.[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:17]-[C;H0;+0:4](=[*:5])-[*:6].[*:7]-[n+;H0:8]1:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:[cH;+0:13]:[cH;+0:14]:1.[OH2;+0:16] |
Reaction | ![]() |
Core-to-Core | |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone. | Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE | 2011 Mar 15 | 21250661 |