Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.182
Description:2-heptyl-3-hydroxy-4(1H)-quinolone synthase.
Alternative Name: 2-heptyl-3,4-dihydroxyquinoline synthase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.182
BRENDA Enzyme Link: BRENDA 1.14.13.182
KEGG Enzyme Link: KEGG1.14.13.182
BioCyc Enzyme Link: BioCyc 1.14.13.182
ExPASy Enzyme Link: ExPASy1.14.13.182
EC2PDB Enzyme Link: EC2PDB 1.14.13.182
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.182
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.182
IntEnz Enzyme Link: IntEnz 1.14.13.182
MEDLINE Enzyme Link: MEDLINE 1.14.13.182
MSA:

1.14.13.182;

Phylogenetic Tree:

1.14.13.182;

Uniprot:
M-CSA:
RHEA:37871 2-heptyl-4-quinolone + H(+) + NADH + O2 = 2-heptyl-3-hydroxy-4(1H)-quinolone + H2O + NAD(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14]
Reaction
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References

TitleAuthorsDatePubMed ID
Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH.Schertzer JW, Brown SA, Whiteley M2010 Sep20662781