EC number:1.14.13.187
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.187 |
|---|---|
| Description: | L-evernosamine nitrososynthase. |
| Cath: | 1.10.540.10; 1.20.140.10; 2.40.110.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.187 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.187 |
| KEGG Enzyme Link: | KEGG1.14.13.187 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.187 |
| ExPASy Enzyme Link: | ExPASy1.14.13.187 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.187 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.187 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.187 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.187 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.187 |
EC number:1.14.13.187
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:40555 | dTDP-beta-L-evernosamine + H(+) + 2 NADPH + 2 O2 = dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 3 H2O + 2 NADP(+) |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[N;H0;+0:4](-[*:5])-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-1.[*:9]-[N;H0;+0:10]1-[CH;+0:11]=[C;H0;+0:12](-[*:13])-[CH2;+0:14]-[CH;+0:15]=[CH;+0:16]-1.[*:17]-[NH2;+0:18].[H+;H0:19].[O;H0;+0:20]=[O;H0;+0:21].[O;H0;+0:22]=[O;H0;+0:23]>>[*:17]-[N;H0;+0:18]=[O;H0;+0:20].[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[n+;H0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]-[n+;H0:10]1:[cH;+0:11]:[c;H0;+0:12](-[*:13]):[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:1.[OH2;+0:21].[OH2;+0:22].[OH2;+0:23] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis . | Vey JL, Al-Mestarihi A, Hu Y, Funk MA, Bachmann BO, Iverson TM | 2010 Nov 2 | 20866105 |
| A unifying nitrososynthase involved in nitrosugar biosynthesis. | Hu Y, Al-Mestarihi A, Grimes CL, Kahne D, Bachmann BO | 2008 Nov 26 | 18983146 |