EC number:1.14.13.212
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.212 |
|---|---|
| Description: | 1,3,7-trimethyluric acid 5-monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.212 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.212 |
| KEGG Enzyme Link: | KEGG1.14.13.212 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.212 |
| ExPASy Enzyme Link: | ExPASy1.14.13.212 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.212 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.212 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.212 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.212 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.212 |
EC number:1.14.13.212
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:48992 | 1,3,7-trimethylurate + H(+) + NADH + O2 = 1,3,7-trimethyl-5-hydroxyisourate + H2O + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[c;H0;+0:10]1:[nH;+0:11]:[c;H0;+0:12]2:[c;H0;+0:13](:[c;H0;+0:14](=[*:15]):[n;H0;+0:16](-[*:17]):[c;H0;+0:18](=[*:19]):[n;H0;+0:20]:2-[*:21]):[n;H0;+0:22]:1-[*:23].[H+;H0:24].[O;H0;+0:25]=[O;H0;+0:26]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]=[C;H0;+0:10]1-[N;H0;+0:11]=[C;H0;+0:12]2-[N;H0;+0:20](-[*:21])-[C;H0;+0:18](=[*:19])-[N;H0;+0:16](-[*:17])-[C;H0;+0:14](=[*:15])-[C;H0;+0:13]-2(-[OH;+0:25])-[N;H0;+0:22]-1-[*:23].[OH2;+0:26] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Genetic characterization of caffeine degradation by bacteria and its potential applications. | Summers RM, Mohanty SK, Gopishetty S, Subramanian M | 2015 May | 25678373 |
| Delineation of the caffeine C-8 oxidation pathway in Pseudomonas sp. strain CBB1 via characterization of a new trimethyluric acid monooxygenase and genes involved in trimethyluric acid metabolism. | Mohanty SK, Yu CL, Das S, Louie TM, Gakhar L, Subramanian M | 2012 Aug | 22609920 |