EC number:1.14.13.217
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.217 |
|---|---|
| Description: | Protodeoxyviolaceinate monooxygenase. |
| Alternative Name: |
Protoviolaceinate synthase. |
| Cath: | 3.30.9.20; 3.50.50.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.217 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.217 |
| KEGG Enzyme Link: | KEGG1.14.13.217 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.217 |
| ExPASy Enzyme Link: | ExPASy1.14.13.217 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.217 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.217 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.217 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.217 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.217 |
EC number:1.14.13.217
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:49124 | H(+) + NADPH + O2 + protodeoxyviolaceinate = H2O + NADP(+) + protoviolaceinate |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Violacein and related tryptophan metabolites produced by Chromobacterium violaceum: biosynthetic mechanism and pathway for construction of violacein core. | Hoshino T | 2011 Sep | 21779844 |
| Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function. | Shinoda K, Hasegawa T, Sato H, Shinozaki M, Kuramoto H, Takamiya Y, Sato T, Nikaidou N, Watanabe T, Hoshino T | 2007 Oct 28 | 17925955 |
| In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum. | Balibar CJ, Walsh CT | 2006 Dec 26 | 17176066 |
| RHEA:49372 | H(+) + NADH + O2 + protodeoxyviolaceinate = H2O + NAD(+) + protoviolaceinate |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Violacein and related tryptophan metabolites produced by Chromobacterium violaceum: biosynthetic mechanism and pathway for construction of violacein core. | Hoshino T | 2011 Sep | 21779844 |
| Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function. | Shinoda K, Hasegawa T, Sato H, Shinozaki M, Kuramoto H, Takamiya Y, Sato T, Nikaidou N, Watanabe T, Hoshino T | 2007 Oct 28 | 17925955 |
| In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum. | Balibar CJ, Walsh CT | 2006 Dec 26 | 17176066 |
| RHEA:49748 | 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate = CO2 + 2 H2O + NADP(+) + proviolacein |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[OH;+0:11])-[c;H0;+0:12]1:[nH;+0:13]:[c;H0;+0:14](-[c;H0;+0:15](:[*:16]):[*:17]:[*:18]:[cH;+0:19]:[*:20]):[cH;+0:21]:[c;H0;+0:22]:1-[c;H0;+0:23](:[*:24]):[*:25].[H+;H0:26].[H+;H0:27].[O;H0;+0:28]=[O;H0;+0:29].[O;H0;+0:30]=[O;H0;+0:31]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:24]:[c;H0;+0:23](:[*:25])-[C;H0;+0:22]1=[CH;+0:21]-[C;H0;+0:14](-[c;H0;+0:15](:[*:16]):[*:17]:[*:18]:[c;H0;+0:19](:[*:20])-[OH;+0:29])=[N;H0;+0:13]-[C;H0;+0:12]-1=[O;H0;+0:28].[*:9]=[C;H0;+0:10]=[O;H0;+0:11].[OH2;+0:30].[OH2;+0:31] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Violacein and related tryptophan metabolites produced by Chromobacterium violaceum: biosynthetic mechanism and pathway for construction of violacein core. | Hoshino T | 2011 Sep | 21779844 |
| Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function. | Shinoda K, Hasegawa T, Sato H, Shinozaki M, Kuramoto H, Takamiya Y, Sato T, Nikaidou N, Watanabe T, Hoshino T | 2007 Oct 28 | 17925955 |
| In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum. | Balibar CJ, Walsh CT | 2006 Dec 26 | 17176066 |
| RHEA:49752 | 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate = CO2 + 2 H2O + NAD(+) + proviolacein |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[OH;+0:11])-[c;H0;+0:12]1:[nH;+0:13]:[c;H0;+0:14](-[c;H0;+0:15](:[*:16]):[*:17]:[*:18]:[cH;+0:19]:[*:20]):[cH;+0:21]:[c;H0;+0:22]:1-[c;H0;+0:23](:[*:24]):[*:25].[H+;H0:26].[H+;H0:27].[O;H0;+0:28]=[O;H0;+0:29].[O;H0;+0:30]=[O;H0;+0:31]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:24]:[c;H0;+0:23](:[*:25])-[C;H0;+0:22]1=[CH;+0:21]-[C;H0;+0:14](-[c;H0;+0:15](:[*:16]):[*:17]:[*:18]:[c;H0;+0:19](:[*:20])-[OH;+0:29])=[N;H0;+0:13]-[C;H0;+0:12]-1=[O;H0;+0:28].[*:9]=[C;H0;+0:10]=[O;H0;+0:11].[OH2;+0:30].[OH2;+0:31] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Violacein and related tryptophan metabolites produced by Chromobacterium violaceum: biosynthetic mechanism and pathway for construction of violacein core. | Hoshino T | 2011 Sep | 21779844 |
| Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function. | Shinoda K, Hasegawa T, Sato H, Shinozaki M, Kuramoto H, Takamiya Y, Sato T, Nikaidou N, Watanabe T, Hoshino T | 2007 Oct 28 | 17925955 |
| In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum. | Balibar CJ, Walsh CT | 2006 Dec 26 | 17176066 |
| RHEA:49756 | H(+) + O2 + protoviolaceinate = CO2 + H2O + proviolacein |
| RULE(radius=1) | [*:1]:[c;H0;+0:2](:[*:3])-[c;H0;+0:4]1:[cH;+0:5]:[c;H0;+0:6](-[c;H0;+0:7](:[*:8]):[*:9]):[nH;+0:10]:[c;H0;+0:11]:1-[C;H0;+0:12](=[*:13])-[OH;+0:14].[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]:[c;H0;+0:2](:[*:3])-[C;H0;+0:4]1=[CH;+0:5]-[C;H0;+0:6](-[c;H0;+0:7](:[*:8]):[*:9])=[N;H0;+0:10]-[C;H0;+0:11]-1=[O;H0;+0:16].[*:13]=[C;H0;+0:12]=[O;H0;+0:14].[OH2;+0:17] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Violacein and related tryptophan metabolites produced by Chromobacterium violaceum: biosynthetic mechanism and pathway for construction of violacein core. | Hoshino T | 2011 Sep | 21779844 |
| Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function. | Shinoda K, Hasegawa T, Sato H, Shinozaki M, Kuramoto H, Takamiya Y, Sato T, Nikaidou N, Watanabe T, Hoshino T | 2007 Oct 28 | 17925955 |
| In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from Chromobacterium violaceum. | Balibar CJ, Walsh CT | 2006 Dec 26 | 17176066 |