EC number:1.14.13.218
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.218 |
|---|---|
| Description: | 5-methylphenazine-1-carboxylate 1-monooxygenase. |
3D structure
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.218 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.218 |
| KEGG Enzyme Link: | KEGG1.14.13.218 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.218 |
| ExPASy Enzyme Link: | ExPASy1.14.13.218 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.218 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.218 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.218 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.218 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.218 |
EC number:1.14.13.218
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:53868 | 2 H(+) + NADH + O2 + phenazine-1-carboxylate = 1-hydroxyphenazine + CO2 + H2O + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[OH;+0:11])-[c;H0;+0:12](:[*:13]):[*:14].[H+;H0:15].[H+;H0:16].[O;H0;+0:17]=[O;H0;+0:18]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:13]:[c;H0;+0:12](:[*:14])-[OH;+0:17].[*:9]=[C;H0;+0:10]=[O;H0;+0:11].[OH2;+0:18] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of the pyocyanin biosynthetic protein PhzS. | Greenhagen BT, Shi K, Robinson H, Gamage S, Bera AK, Ladner JE, Parsons JF | 2008 May 13 | 18416536 |
| Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. | Parsons JF, Greenhagen BT, Shi K, Calabrese K, Robinson H, Ladner JE | 2007 Feb 20 | 17253782 |
| Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1. | Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS | 2001 Nov | 11591691 |
| RHEA:48976 | 5-methyl-phenazine-1-carboxylate + 2 H(+) + NADH + O2 = CO2 + H2O + NAD(+) + pyocyanin |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[OH;+0:11])-[c;H0;+0:12](:[*:13]):[*:14].[H+;H0:15].[H+;H0:16].[O;H0;+0:17]=[O;H0;+0:18]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:13]:[c;H0;+0:12](:[*:14])-[OH;+0:17].[*:9]=[C;H0;+0:10]=[O;H0;+0:11].[OH2;+0:18] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of the pyocyanin biosynthetic protein PhzS. | Greenhagen BT, Shi K, Robinson H, Gamage S, Bera AK, Ladner JE, Parsons JF | 2008 May 13 | 18416536 |
| Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa. | Parsons JF, Greenhagen BT, Shi K, Calabrese K, Robinson H, Ladner JE | 2007 Feb 20 | 17253782 |
| Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1. | Mavrodi DV, Bonsall RF, Delaney SM, Soule MJ, Phillips G, Thomashow LS | 2001 Nov | 11591691 |