EC number:1.14.13.222
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.222 |
|---|---|
| Description: | Aurachin C monooxygenase/isomerase. |
| Alternative Name: |
Aurachin C monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.222 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.222 |
| KEGG Enzyme Link: | KEGG1.14.13.222 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.222 |
| ExPASy Enzyme Link: | ExPASy1.14.13.222 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.222 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.222 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.222 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.222 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.222 |
EC number:1.14.13.222
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:49004 | aurachin C + H(+) + NADPH + O2 = 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + H2O + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[c;H0;+0:10]1:[c;H0;+0:11](:[cH;+0:12]:[*:13]):[c;H0;+0:14](:[*:15]):[n;H0;+0:16](-[*:17]):[c;H0;+0:18](-[CH3;+0:19]):[c;H0;+0:20]:1-[*:21].[H+;H0:22].[O;H0;+0:23]=[O;H0;+0:24]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]=[C;H0;+0:10]1-[C;H0;+0:11](-[CH3;+0:19])=[N+;H0:16](-[*:17])-[c;H0;+0:14](:[*:15]):[c;H0;+0:18](:[cH;+0:12]:[*:13])-[C;H0;+0:20]-1(-[*:21])-[OH;+0:23].[OH2;+0:24] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A semipinacol rearrangement directed by an enzymatic system featuring dual-function FAD-dependent monooxygenase. | Katsuyama Y, Harmrolfs K, Pistorius D, Li Y, Müller R | 2012 Sep 10 | 22907798 |
| RHEA:49000 | aurachin C + H(+) + NADH + O2 = 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + H2O + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[c;H0;+0:10]1:[c;H0;+0:11](:[cH;+0:12]:[*:13]):[c;H0;+0:14](:[*:15]):[n;H0;+0:16](-[*:17]):[c;H0;+0:18](-[CH3;+0:19]):[c;H0;+0:20]:1-[*:21].[H+;H0:22].[O;H0;+0:23]=[O;H0;+0:24]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]=[C;H0;+0:10]1-[C;H0;+0:11](-[CH3;+0:19])=[N+;H0:16](-[*:17])-[c;H0;+0:14](:[*:15]):[c;H0;+0:18](:[cH;+0:12]:[*:13])-[C;H0;+0:20]-1(-[*:21])-[OH;+0:23].[OH2;+0:24] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A semipinacol rearrangement directed by an enzymatic system featuring dual-function FAD-dependent monooxygenase. | Katsuyama Y, Harmrolfs K, Pistorius D, Li Y, Müller R | 2012 Sep 10 | 22907798 |