EC number:1.14.13.232

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.232
Description:6-methylpretetramide 4-monooxygenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.232
BRENDA Enzyme Link: BRENDA 1.14.13.232
KEGG Enzyme Link: KEGG1.14.13.232
BioCyc Enzyme Link: BioCyc 1.14.13.232
ExPASy Enzyme Link: ExPASy1.14.13.232
EC2PDB Enzyme Link: EC2PDB 1.14.13.232
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.232
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.232
IntEnz Enzyme Link: IntEnz 1.14.13.232
MEDLINE Enzyme Link: MEDLINE 1.14.13.232

EC number:1.14.13.232

MSA:

1.14.13.232;
Phylogenetic Tree:

1.14.13.232;
Uniprot:
M-CSA:
RHEA:50008 6-methylpretetramide + 2 H(+) + NADPH + O2 = 4-hydroxy-6-methylpretetramide + H2O + NADP(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[H+;H0:13].[O;H0;+0:14]=[O;H0;+0:15]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:14].[OH2;+0:15]
Reaction
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References

TitleAuthorsDatePubMed ID
Identification of OxyE as an ancillary oxygenase during tetracycline biosynthesis.Wang P, Zhang W, Zhan J, Tang Y2009 Jun 1519472250
Identifying the minimal enzymes required for anhydrotetracycline biosynthesis.Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J2008 May 1418422316