EC number:1.14.13.238
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.238 |
|---|---|
| Description: | Dimethylamine monooxygenase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.238 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.238 |
| KEGG Enzyme Link: | KEGG1.14.13.238 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.238 |
| ExPASy Enzyme Link: | ExPASy1.14.13.238 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.238 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.238 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.238 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.238 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.238 |
EC number:1.14.13.238
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:54828 | dimethylamine + H(+) + NADPH + O2 = formaldehyde + H2O + methylamine + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]-[NH;+0:10]-[CH3;+0:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:9]-[NH2;+0:10].[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[CH2;+0:11]=[O;H0;+0:13].[OH2;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Microbial oxidation of amines. Partial purification of a mixed-function secondary-amine oxidase system from Pseudomonas aminovorans that contains an enzymically active cytochrome-P-420-type haemoprotein. | Eady RR, Jarman TR, Large PJ | 1971 Nov | 4401380 |
| Bacterial oxidation of dimethylamine, a new mono-oxygenase reaction. | Eady RR, Large PJ | 1969 Mar | 4389011 |
| Purification to homogeneity and initial physical characterization of secondary amine monooxygenase. | Alberta JA, Dawson JH | 1987 Aug 25 | 3624236 |
| Identification of dimethylamine monooxygenase in marine bacteria reveals a metabolic bottleneck in the methylated amine degradation pathway. | Lidbury I, Mausz MA, Scanlan DJ, Chen Y | 2017 Jul | 28304370 |