Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.241
Description:5-pyridoxate monooxygenase.
Alternative Name: 5-pyridoxate oxidase.
5-pyridoxate dioxygenase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.241
BRENDA Enzyme Link: BRENDA 1.14.13.241
KEGG Enzyme Link: KEGG1.14.13.241
BioCyc Enzyme Link: BioCyc 1.14.13.241
ExPASy Enzyme Link: ExPASy1.14.13.241
EC2PDB Enzyme Link: EC2PDB 1.14.13.241
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.241
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.241
IntEnz Enzyme Link: IntEnz 1.14.13.241
MEDLINE Enzyme Link: MEDLINE 1.14.13.241
MSA:

1.14.13.241;

Phylogenetic Tree:

1.14.13.241;

Uniprot:
M-CSA:
RHEA:11152 5-pyridoxate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]-[c;H0;+0:10]1:[cH;+0:11]:[n;H0;+0:12]:[c;H0;+0:13](-[*:14]):[c;H0;+0:15](-[OH;+0:16]):[c;H0;+0:17]:1-[*:18].[O;H0;+0:19]=[O;H0;+0:20]>>[*:9]-[C;H0;+0:10](=[CH;+0:11]-[NH;+0:12]-[C;H0;+0:13](-[*:14])=[O;H0;+0:19])-[CH;+0:17](-[*:18])-[C;H0;+0:15](=[O;H0;+0:16])-[OH;+0:20].[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1
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References

TitleAuthorsDatePubMed ID
Enzymes of vitamin B6 degradation. Purification and properties of 5-pyridoxic-acid oxygenase from Arthrobacter sp.Nelson MJ, Snell EE1986 Nov 153771566
Flavoenzymes catalyzing oxidative aromatic ring-cleavage reactions.Chaiyen P2010 Jan 119728986
The bacterial oxidation of vitamin B6. VII. Purification, properties, and mechanism of action of an oxygenase which cleaves the 3-hydroxypyridine ring.Sparrow LG, Ho PP, Sundaram TK, Zach D, Nyns EJ, Snell EE1969 May 254306031