| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.241 |
|---|---|
| Description: | 5-pyridoxate monooxygenase. |
| Alternative Name: |
5-pyridoxate oxidase. 5-pyridoxate dioxygenase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.13.241 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.241 |
| KEGG Enzyme Link: | KEGG1.14.13.241 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.241 |
| ExPASy Enzyme Link: | ExPASy1.14.13.241 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.241 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.241 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.241 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.241 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.241 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:11152 | 5-pyridoxate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]-[c;H0;+0:10]1:[cH;+0:11]:[n;H0;+0:12]:[c;H0;+0:13](-[*:14]):[c;H0;+0:15](-[OH;+0:16]):[c;H0;+0:17]:1-[*:18].[O;H0;+0:19]=[O;H0;+0:20]>>[*:9]-[C;H0;+0:10](=[CH;+0:11]-[NH;+0:12]-[C;H0;+0:13](-[*:14])=[O;H0;+0:19])-[CH;+0:17](-[*:18])-[C;H0;+0:15](=[O;H0;+0:16])-[OH;+0:20].[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1 |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Enzymes of vitamin B6 degradation. Purification and properties of 5-pyridoxic-acid oxygenase from Arthrobacter sp. | Nelson MJ, Snell EE | 1986 Nov 15 | 3771566 |
| Flavoenzymes catalyzing oxidative aromatic ring-cleavage reactions. | Chaiyen P | 2010 Jan 1 | 19728986 |
| The bacterial oxidation of vitamin B6. VII. Purification, properties, and mechanism of action of an oxygenase which cleaves the 3-hydroxypyridine ring. | Sparrow LG, Ho PP, Sundaram TK, Zach D, Nyns EJ, Snell EE | 1969 May 25 | 4306031 |