EC number:1.14.13.34

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.34
Description:Leukotriene-E(4) 20-monooxygenase.
Alternative Name: Leukotriene-E(4) omega-hydroxylase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.34
BRENDA Enzyme Link: BRENDA 1.14.13.34
KEGG Enzyme Link: KEGG1.14.13.34
BioCyc Enzyme Link: BioCyc 1.14.13.34
ExPASy Enzyme Link: ExPASy1.14.13.34
EC2PDB Enzyme Link: EC2PDB 1.14.13.34
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.34
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.34
IntEnz Enzyme Link: IntEnz 1.14.13.34
MEDLINE Enzyme Link: MEDLINE 1.14.13.34

EC number:1.14.13.34

MSA:

1.14.13.34;
Phylogenetic Tree:

1.14.13.34;
Uniprot:
M-CSA:
RHEA:24120 H(+) + leukotriene E4 + NADPH + O2 = 20-hydroxy-leukotriene E4 + H2O + NADP(+)
RULE(radius=1) [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH;+0:9]=[CH;+0:10]-1.[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[CH2;+0:2]-[OH;+0:12].[*:3]-[n+;H0:4]1:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:1.[OH2;+0:13]
Reaction
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References

TitleAuthorsDatePubMed ID
Omega-oxidation of cysteine-containing leukotrienes by rat-liver microsomes. Isolation and characterization of omega-hydroxy and omega-carboxy metabolites of leukotriene E4 and N-acetylleukotriene E4.Orning L1987 Dec 302826163