EC number:1.14.13.83
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.13.83 |
|---|---|
| Description: | Precorrin-3B synthase. |
| Alternative Name: |
Precorrin-3X synthase. |
| Cath: | 3.30.950.10; 3.40.1010.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.13.83 |
| BRENDA Enzyme Link: | BRENDA 1.14.13.83 |
| KEGG Enzyme Link: | KEGG1.14.13.83 |
| BioCyc Enzyme Link: | BioCyc 1.14.13.83 |
| ExPASy Enzyme Link: | ExPASy1.14.13.83 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.13.83 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.13.83 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.13.83 |
| IntEnz Enzyme Link: | IntEnz 1.14.13.83 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.13.83 |
EC number:1.14.13.83
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:17293 | 2 H(+) + NADH + O2 + precorrin-3A = H2O + NAD(+) + precorrin-3B |
| RULE(radius=1) | ([*:1]-[C;H0;+0:2](-[*:3])=[C;H0;+0:4](-[*:5])-[*:6].[*:7]-[OH;+0:8]).[*:9]-[C;H0;+0:10]1=[CH;+0:11]-[N;H0;+0:12](-[*:13])-[CH;+0:14]=[CH;+0:15]-[CH2;+0:16]-1.[H+;H0:17].[H+;H0:18].[O;H0;+0:19]=[O;H0;+0:20]>>[*:1]-[C;H0;+0:2](-[*:3])(-[O;H0;+0:8]-[*:7])-[C;H0;+0:4](-[*:5])(-[*:6])-[OH;+0:19].[*:9]-[c;H0;+0:10]1:[cH;+0:11]:[n+;H0:12](-[*:13]):[cH;+0:14]:[cH;+0:15]:[cH;+0:16]:1.[OH2;+0:20] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Biosynthesis of vitamin B12. Discovery of the enzymes for oxidative ring contraction and insertion of the fourth methyl group. | Scott AI, Roessner CA, Stolowich NJ, Spencer JB, Min C, Ozaki SI | 1993 Sep 27 | 8405386 |
| Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans. | Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F | 1993 Nov | 8226690 |
| The biosynthesis of adenosylcobalamin (vitamin B12). | Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC | 2002 Aug | 12195810 |