EC number:1.14.13.84

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.13.84
Description:4-hydroxyacetophenone monooxygenase.
Alternative Name: HAPMO.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.13.84
BRENDA Enzyme Link: BRENDA 1.14.13.84
KEGG Enzyme Link: KEGG1.14.13.84
BioCyc Enzyme Link: BioCyc 1.14.13.84
ExPASy Enzyme Link: ExPASy1.14.13.84
EC2PDB Enzyme Link: EC2PDB 1.14.13.84
ExplorEnz Enzyme Link: ExplorEnz 1.14.13.84
PRIAM enzyme-specific profiles Link: PRIAM 1.14.13.84
IntEnz Enzyme Link: IntEnz 1.14.13.84
MEDLINE Enzyme Link: MEDLINE 1.14.13.84

EC number:1.14.13.84

MSA:

1.14.13.84;
Phylogenetic Tree:

1.14.13.84;
Uniprot:
M-CSA:
RHEA:22916 4'-hydroxyacetophenone + H(+) + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP(+)
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]=[C;H0;+0:10](-[*:11])-[c;H0;+0:12](:[*:13]):[*:14].[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]=[C;H0;+0:10](-[*:11])-[O;H0;+0:16]-[c;H0;+0:12](:[*:13]):[*:14].[OH2;+0:17]
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References

TitleAuthorsDatePubMed ID
Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase.Kamerbeek NM, Olsthoorn AJ, Fraaije MW, Janssen DB2003 Jan12514023
4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB. A novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds.Kamerbeek NM, Moonen MJ, Van Der Ven JG, Van Berkel WJ, Fraaije MW, Janssen DB2001 May11322873