Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.109
Description:3-hydroxyindolin-2-one monooxygenase.
Alternative Name: CYP71C1.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.109
BRENDA Enzyme Link: BRENDA 1.14.14.109
KEGG Enzyme Link: KEGG1.14.14.109
BioCyc Enzyme Link: BioCyc 1.14.14.109
ExPASy Enzyme Link: ExPASy1.14.14.109
EC2PDB Enzyme Link: EC2PDB 1.14.14.109
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.109
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.109
IntEnz Enzyme Link: IntEnz 1.14.14.109
MEDLINE Enzyme Link: MEDLINE 1.14.14.109
MSA:

1.14.14.109;

Phylogenetic Tree:

1.14.14.109;

Uniprot:
M-CSA:
RHEA:31927 3-hydroxyindolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[c;H0;+0:10]1:[c;H0;+0:11](:[*:12])-[CH;+0:13](-[*:14])-[*:15]-[NH;+0:16]-1.[H+;H0:17].[O;H0;+0:18]=[O;H0;+0:19]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10]1:[c;H0;+0:11](:[*:12])-[NH;+0:16]-[*:15]-[CH;+0:13](-[*:14])-[O;H0;+0:19]-1.[OH2;+0:18]
Reaction
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References

TitleAuthorsDatePubMed ID
Analysis of a chemical plant defense mechanism in grasses.Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A1997 Aug 19235894
Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays.Spiteller P, Glawischnig E, Gierl A, Steglich W2001 Jun11393516
Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses.Glawischnig E, Grün S, Frey M, Gierl A1999 Mar10385992