EC Tree |
1. Oxidoreductases |
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
ID: | 1.14.14.109 |
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Description: | 3-hydroxyindolin-2-one monooxygenase. |
Alternative Name: |
CYP71C1. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.14.14.109 |
BRENDA Enzyme Link: | BRENDA 1.14.14.109 |
KEGG Enzyme Link: | KEGG1.14.14.109 |
BioCyc Enzyme Link: | BioCyc 1.14.14.109 |
ExPASy Enzyme Link: | ExPASy1.14.14.109 |
EC2PDB Enzyme Link: | EC2PDB 1.14.14.109 |
ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.109 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.109 |
IntEnz Enzyme Link: | IntEnz 1.14.14.109 |
MEDLINE Enzyme Link: | MEDLINE 1.14.14.109 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:31927 | 3-hydroxyindolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[c;H0;+0:10]1:[c;H0;+0:11](:[*:12])-[CH;+0:13](-[*:14])-[*:15]-[NH;+0:16]-1.[H+;H0:17].[O;H0;+0:18]=[O;H0;+0:19]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10]1:[c;H0;+0:11](:[*:12])-[NH;+0:16]-[*:15]-[CH;+0:13](-[*:14])-[O;H0;+0:19]-1.[OH2;+0:18] |
Reaction | ![]() |
Core-to-Core | |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Analysis of a chemical plant defense mechanism in grasses. | Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A | 1997 Aug 1 | 9235894 |
Studies on the biosynthesis of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) from 3-hydroxyindolin-2-one in Zea mays. | Spiteller P, Glawischnig E, Gierl A, Steglich W | 2001 Jun | 11393516 |
Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses. | Glawischnig E, Grün S, Frey M, Gierl A | 1999 Mar | 10385992 |