EC number:1.14.14.112
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.112 |
|---|---|
| Description: | Ent-cassa-12,15-diene 11-hydroxylase. |
| Alternative Name: |
Ent-cassadiene C11-alpha-hydroxylase. CYP76M7. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.112 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.112 |
| KEGG Enzyme Link: | KEGG1.14.14.112 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.112 |
| ExPASy Enzyme Link: | ExPASy1.14.14.112 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.112 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.112 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.112 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.112 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.112 |
EC number:1.14.14.112
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:31967 | ent-cassa-12,15-diene + O2 + reduced [NADPH--hemoprotein reductase] = ent-11beta-hydroxycassa-12,15-diene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH2;+0:9]-[CH;+0:10]=[CH;+0:11]-1.[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:13].[*:4]-[n+;H0:5]1:[cH;+0:6]:[c;H0;+0:7](-[*:8]):[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:1.[OH2;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster. | Wang Q, Hillwig ML, Okada K, Yamazaki K, Wu Y, Swaminathan S, Yamane H, Peters RJ | 2012 Feb 24 | 22215681 |
| Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7. | Wu Y, Hillwig ML, Wang Q, Peters RJ | 2011 Nov 4 | 21985968 |
| CYP76M7 is an ent-cassadiene C11alpha-hydroxylase defining a second multifunctional diterpenoid biosynthetic gene cluster in rice. | Swaminathan S, Morrone D, Wang Q, Fulton DB, Peters RJ | 2009 Oct | 19825834 |