Enzyme

Download
EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.115
Description:11-oxo-beta-amyrin 30-oxidase.
Alternative Name: CYP72A154.
CYP72A.
11-oxo-beta-amyrin 30-monooxygenase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.115
BRENDA Enzyme Link: BRENDA 1.14.14.115
KEGG Enzyme Link: KEGG1.14.14.115
BioCyc Enzyme Link: BioCyc 1.14.14.115
ExPASy Enzyme Link: ExPASy1.14.14.115
EC2PDB Enzyme Link: EC2PDB 1.14.14.115
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.115
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.115
IntEnz Enzyme Link: IntEnz 1.14.14.115
MEDLINE Enzyme Link: MEDLINE 1.14.14.115
MSA:

1.14.14.115;

Phylogenetic Tree:

1.14.14.115;

Uniprot:
M-CSA:
RHEA:35499 11-oxo-beta-amyrin + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = glycyrrhetinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH;+0:9]=[CH;+0:10]-1.[H+;H0:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:13])-[OH;+0:14].[*:3]-[n+;H0:4]1:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:1
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin.Seki H, Sawai S, Ohyama K, Mizutani M, Ohnishi T, Sudo H, Fukushima EO, Akashi T, Aoki T, Saito K, Muranaka T2011 Nov22128119