| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.115 |
|---|---|
| Description: | 11-oxo-beta-amyrin 30-oxidase. |
| Alternative Name: |
CYP72A154. CYP72A. 11-oxo-beta-amyrin 30-monooxygenase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.14.115 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.115 |
| KEGG Enzyme Link: | KEGG1.14.14.115 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.115 |
| ExPASy Enzyme Link: | ExPASy1.14.14.115 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.115 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.115 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.115 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.115 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.115 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:35499 | 11-oxo-beta-amyrin + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = glycyrrhetinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH;+0:9]=[CH;+0:10]-1.[H+;H0:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:13])-[OH;+0:14].[*:3]-[n+;H0:4]1:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:1 |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin. | Seki H, Sawai S, Ohyama K, Mizutani M, Ohnishi T, Sudo H, Fukushima EO, Akashi T, Aoki T, Saito K, Muranaka T | 2011 Nov | 22128119 |