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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

ID:	1.14.14.118
Description:	Tryprostatin B 6-hydroxylase.

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UniProtKB Enzyme Link:	UniProtKB 1.14.14.118
BRENDA Enzyme Link:	BRENDA 1.14.14.118
KEGG Enzyme Link:	KEGG1.14.14.118
BioCyc Enzyme Link:	BioCyc 1.14.14.118
ExPASy Enzyme Link:	ExPASy1.14.14.118
EC2PDB Enzyme Link:	EC2PDB 1.14.14.118
ExplorEnz Enzyme Link:	ExplorEnz 1.14.14.118
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.14.118
IntEnz Enzyme Link:	IntEnz 1.14.14.118
MEDLINE Enzyme Link:	MEDLINE 1.14.14.118

RHEA:35955	O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin B = 6-hydroxytryprostatin B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1)	[:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[:9]:[cH;+0:10]:[:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[:9]:[c;H0;+0:10](:[:11])-[OH;+0:13].[OH2;+0:14]
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Title	Authors	Date	PubMed ID
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.	Kato N, Suzuki H, Takagi H, Asami Y, Kakeya H, Uramoto M, Usui T, Takahashi S, Sugimoto Y, Osada H	2009 Mar 23	19226505