EC number:1.14.14.119

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.119
Description:Fumitremorgin C monooxygenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.119
BRENDA Enzyme Link: BRENDA 1.14.14.119
KEGG Enzyme Link: KEGG1.14.14.119
BioCyc Enzyme Link: BioCyc 1.14.14.119
ExPASy Enzyme Link: ExPASy1.14.14.119
EC2PDB Enzyme Link: EC2PDB 1.14.14.119
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.119
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.119
IntEnz Enzyme Link: IntEnz 1.14.14.119
MEDLINE Enzyme Link: MEDLINE 1.14.14.119

EC number:1.14.14.119

MSA:

1.14.14.119;
Phylogenetic Tree:

1.14.14.119;
Uniprot:
M-CSA:
RHEA:35967 fumitremorgin C + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 12alpha,13alpha-dihydroxyfumitremorgin C + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH;+0:2](-[*:3])-[CH2;+0:4]-[*:5].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[C;H0;+0:9](-[*:10])-[CH2;+0:11]-[CH;+0:12]=[CH;+0:13]-1.[H+;H0:14].[H+;H0:15].[O;H0;+0:16]=[O;H0;+0:17].[O;H0;+0:18]=[O;H0;+0:19]>>[*:1]-[C;H0;+0:2](-[*:3])(-[OH;+0:17])-[CH;+0:4](-[*:5])-[OH;+0:16].[*:6]-[n+;H0:7]1:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:[cH;+0:12]:[cH;+0:13]:1.[OH2;+0:18].[OH2;+0:19]
Reaction
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References

TitleAuthorsDatePubMed ID
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.Kato N, Suzuki H, Takagi H, Asami Y, Kakeya H, Uramoto M, Usui T, Takahashi S, Sugimoto Y, Osada H2009 Mar 2319226505