| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.122 |
|---|---|
| Description: | Oryzalexin E synthase. |
| Alternative Name: |
CYP76M6. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.14.122 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.122 |
| KEGG Enzyme Link: | KEGG1.14.14.122 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.122 |
| ExPASy Enzyme Link: | ExPASy1.14.14.122 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.122 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.122 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.122 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.122 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.122 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:41468 | ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oryzalexin E + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[*:4].[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[C;H0;+0:8](-[*:9])-[CH2;+0:10]-[CH;+0:11]=[CH;+0:12]-1.[H+;H0:13].[O;H0;+0:14]=[O;H0;+0:15]>>[*:1]-[C;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:14].[*:5]-[n+;H0:6]1:[cH;+0:7]:[c;H0;+0:8](-[*:9]):[cH;+0:10]:[cH;+0:11]:[cH;+0:12]:1.[OH2;+0:15] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis. | Wu Y, Wang Q, Hillwig ML, Peters RJ | 2013 Sep 1 | 23795884 |
| Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster. | Wang Q, Hillwig ML, Okada K, Yamazaki K, Wu Y, Swaminathan S, Yamane H, Peters RJ | 2012 Feb 24 | 22215681 |