EC number:1.14.14.126

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.126
Description:Beta-amyrin 28-monooxygenase.
Alternative Name: CYP716A52v2.
CYP716A12.
CYP16A75.
Beta-amyrin 28-oxidase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.126
BRENDA Enzyme Link: BRENDA 1.14.14.126
KEGG Enzyme Link: KEGG1.14.14.126
BioCyc Enzyme Link: BioCyc 1.14.14.126
ExPASy Enzyme Link: ExPASy1.14.14.126
EC2PDB Enzyme Link: EC2PDB 1.14.14.126
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.126
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.126
IntEnz Enzyme Link: IntEnz 1.14.14.126
MEDLINE Enzyme Link: MEDLINE 1.14.14.126

EC number:1.14.14.126

MSA:

1.14.14.126;
Phylogenetic Tree:

1.14.14.126;
Uniprot:
M-CSA:
RHEA:43068 beta-amyrin + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 4 H(+) + 4 H2O + oleanolate + 3 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH;+0:9]=[CH;+0:10]-1.[H+;H0:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:13])-[OH;+0:14].[*:3]-[n+;H0:4]1:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:1
Reaction
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References

TitleAuthorsDatePubMed ID
The involvement of β-amyrin 28-oxidase (CYP716A52v2) in oleanane-type ginsenoside biosynthesis in Panax ginseng.Han JY, Kim MJ, Ban YW, Hwang HS, Choi YE2013 Dec24092881
CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis.Fukushima EO, Seki H, Ohyama K, Ono E, Umemoto N, Mizutani M, Saito K, Muranaka T2011 Dec22039103