EC number:1.14.14.127

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.127
Description:Methyl farnesoate epoxidase.
Alternative Name: CYP15A1.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.127
BRENDA Enzyme Link: BRENDA 1.14.14.127
KEGG Enzyme Link: KEGG1.14.14.127
BioCyc Enzyme Link: BioCyc 1.14.14.127
ExPASy Enzyme Link: ExPASy1.14.14.127
EC2PDB Enzyme Link: EC2PDB 1.14.14.127
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.127
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.127
IntEnz Enzyme Link: IntEnz 1.14.14.127
MEDLINE Enzyme Link: MEDLINE 1.14.14.127

EC number:1.14.14.127

MSA:

1.14.14.127;
Phylogenetic Tree:

1.14.14.127;
Uniprot:
M-CSA:
RHEA:43728 methyl (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + juvenile hormone III + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH;+0:2]=[C;H0;+0:3](-[*:4])-[*:5].[*:6]-[N;H0;+0:7]1-[CH;+0:8]=[C;H0;+0:9](-[*:10])-[CH2;+0:11]-[CH;+0:12]=[CH;+0:13]-1.[H+;H0:14].[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]-[CH;+0:2]1-[O;H0;+0:15]-[C;H0;+0:3]-1(-[*:4])-[*:5].[*:6]-[n+;H0:7]1:[cH;+0:8]:[c;H0;+0:9](-[*:10]):[cH;+0:11]:[cH;+0:12]:[cH;+0:13]:1.[OH2;+0:16]
Reaction
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References

TitleAuthorsDatePubMed ID
Function, diversity, and application of insect juvenile hormone epoxidases (CYP15).Daimon T, Shinoda T2013 Jan-Feb23586995
CYP15A1, the cytochrome P450 that catalyzes epoxidation of methyl farnesoate to juvenile hormone III in cockroach corpora allata.Helvig C, Koener JF, Unnithan GC, Feyereisen R2004 Mar 2315024118