EC number:1.14.14.129
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.129 |
|---|---|
| Description: | Long-chain acyl-CoA omega-monooxygenase. |
| Alternative Name: |
Long-chain acyl-CoA omega-hydroxylase. CYP86A22. CYP52M1. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.129 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.129 |
| KEGG Enzyme Link: | KEGG1.14.14.129 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.129 |
| ExPASy Enzyme Link: | ExPASy1.14.14.129 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.129 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.129 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.129 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.129 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.129 |
EC number:1.14.14.129
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:45076 | (9Z,12Z)-octadecadienoyl-CoA + O2 + reduced [NADPH--hemoprotein reductase] = (9Z,12Z)-18-hydroxyoctadecadienoyl-CoA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[N;H0;+0:4](-[*:5])-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-1.[*:9]-[CH3;+0:10].[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:9]-[CH2;+0:10]-[OH;+0:12].[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[n+;H0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[OH2;+0:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The cytochrome P450 CYP86A22 is a fatty acyl-CoA omega-hydroxylase essential for Estolide synthesis in the stigma of Petunia hybrida. | Han J, Clement JM, Li J, King A, Ng S, Jaworski JG | 2010 Feb 5 | 19940120 |
| Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | Huang FC, Peter A, Schwab W | 2014 Jan | 24242247 |
| RHEA:45072 | (9Z)-octadecenoyl-CoA + O2 + reduced [NADPH--hemoprotein reductase] = (9Z)-18-hydroxyoctadecenoyl-CoA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[N;H0;+0:4](-[*:5])-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-1.[*:9]-[CH3;+0:10].[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:9]-[CH2;+0:10]-[OH;+0:12].[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[n+;H0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[OH2;+0:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The cytochrome P450 CYP86A22 is a fatty acyl-CoA omega-hydroxylase essential for Estolide synthesis in the stigma of Petunia hybrida. | Han J, Clement JM, Li J, King A, Ng S, Jaworski JG | 2010 Feb 5 | 19940120 |