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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

ID:	1.14.14.131
Description:	Bursehernin 5'-monooxygenase.
Alternative Name:	CYP71CU1. Bursehernin 5'-hydroxylase.

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UniProtKB Enzyme Link:	UniProtKB 1.14.14.131
BRENDA Enzyme Link:	BRENDA 1.14.14.131
KEGG Enzyme Link:	KEGG1.14.14.131
BioCyc Enzyme Link:	BioCyc 1.14.14.131
ExPASy Enzyme Link:	ExPASy1.14.14.131
EC2PDB Enzyme Link:	EC2PDB 1.14.14.131
ExplorEnz Enzyme Link:	ExplorEnz 1.14.14.131
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.14.131
IntEnz Enzyme Link:	IntEnz 1.14.14.131
MEDLINE Enzyme Link:	MEDLINE 1.14.14.131

RHEA:49028	(-)-bursehernin + O2 + reduced [NADPH--hemoprotein reductase] = (-)-5'-demethylyatein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1)	[:1]-[N;H0;+0:2]1-[:3]:[:4]-[NH;+0:5]-[c;H0;+0:6](:[:7]):[c;H0;+0:8]-1:[nH;+0:9]:[:10].[:11]:[cH;+0:12]:[:13].[O;H0;+0:14]=[O;H0;+0:15]>>[:1]-[n;H0;+0:2]1:[:3]:[:4]:[n;H0;+0:5]:[c;H0;+0:6](:[:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[:10].[:11]:[c;H0;+0:12](:[:13])-[OH;+0:14].[OH2;+0:15]
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Title	Authors	Date	PubMed ID
Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone.	Lau W, Sattely ES	2015 Sep 11	26359402