EC Tree |
1. Oxidoreductases |
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
ID: | 1.14.14.136 | ||
---|---|---|---|
Description: | Deoxysarpagine hydroxylase. | ||
Alternative Name: |
DOSH. | ||
Prosite: | PDOC00081; | ||
PDB: |
|
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.14.14.136 |
BRENDA Enzyme Link: | BRENDA 1.14.14.136 |
KEGG Enzyme Link: | KEGG1.14.14.136 |
BioCyc Enzyme Link: | BioCyc 1.14.14.136 |
ExPASy Enzyme Link: | ExPASy1.14.14.136 |
EC2PDB Enzyme Link: | EC2PDB 1.14.14.136 |
ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.136 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.136 |
IntEnz Enzyme Link: | IntEnz 1.14.14.136 |
MEDLINE Enzyme Link: | MEDLINE 1.14.14.136 |
MSA: | |
---|---|
Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:14237 | 10-deoxysarpagine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sarpagine |
RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
Deoxysarpagine hydroxylase--a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia. | Yu B, Ruppert M, Stöckigt J | 2002 Aug | 12057637 |