Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.136
Description:Deoxysarpagine hydroxylase.
Alternative Name: DOSH.
Prosite: PDOC00081;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.136
BRENDA Enzyme Link: BRENDA 1.14.14.136
KEGG Enzyme Link: KEGG1.14.14.136
BioCyc Enzyme Link: BioCyc 1.14.14.136
ExPASy Enzyme Link: ExPASy1.14.14.136
EC2PDB Enzyme Link: EC2PDB 1.14.14.136
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.136
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.136
IntEnz Enzyme Link: IntEnz 1.14.14.136
MEDLINE Enzyme Link: MEDLINE 1.14.14.136
MSA:

1.14.14.136;

Phylogenetic Tree:

1.14.14.136;

Uniprot:
M-CSA:
RHEA:14237 10-deoxysarpagine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sarpagine
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14]
Reaction
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References

TitleAuthorsDatePubMed ID
Deoxysarpagine hydroxylase--a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia.Yu B, Ruppert M, Stöckigt J2002 Aug12057637