EC number:1.14.14.137
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.137 | ||
|---|---|---|---|
| Description: | (+)-abscisic acid 8'-hydroxylase. | ||
| Alternative Name: |
CYP707A1. ABA 8'-hydroxylase. (+)-ABA 8'-hydroxylase. | ||
| Prosite: | PDOC00081; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.137 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.137 |
| KEGG Enzyme Link: | KEGG1.14.14.137 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.137 |
| ExPASy Enzyme Link: | ExPASy1.14.14.137 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.137 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.137 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.137 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.137 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.137 |
EC number:1.14.14.137
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:12897 | 2-cis-(+)-abscisate + O2 + reduced [NADPH--hemoprotein reductase] = (+)-8'-hydroxyabscisate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH;+0:9]=[CH;+0:10]-1.[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[CH2;+0:2]-[OH;+0:12].[*:3]-[n+;H0:4]1:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:1.[OH2;+0:13] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| (+)-Abscisic acid 8'-hydroxylase is a cytochrome P450 monooxygenase | Krochko JE, Abrams GD, Loewen MK, Abrams SR, Cutler AJ | 1998 Nov | 9808729 |
| Arabidopsis CYP707As encode (+)-abscisic acid 8'-hydroxylase, a key enzyme in the oxidative catabolism of abscisic acid. | Saito S, Hirai N, Matsumoto C, Ohigashi H, Ohta D, Sakata K, Mizutani M | 2004 Apr | 15064374 |