EC number:1.14.14.140
| ID: | 1.14.14.140 | ||
|---|---|---|---|
| Description: | Licodione synthase. | ||
| Alternative Name: |
CYP93B1. (2S)-flavanone 2-hydroxylase. | ||
| Prosite: | PDOC00081; | ||
| PDB: |
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3D structure
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| RHEA:15697 | liquiritigenin + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + licodione + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[c;H0;+0:10](:[*:11])-[O;H0;+0:12]-[CH;+0:13](-[*:14])-[*:15].[O;H0;+0:16]=[O;H0;+0:17]>>([*:14]-[C;H0;+0:13](-[*:15])=[O;H0;+0:12].[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:16]).[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[OH2;+0:17] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification of a cytochrome P450 cDNA encoding (2S)-flavanone 2-hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae) which represents licodione synthase and flavone synthase II. | Akashi T, Aoki T, Ayabe S | 1998 Jul 17 | 9708921 |
| Licodione Synthase, a Cytochrome P450 Monooxygenase Catalyzing 2-Hydroxylation of 5-Deoxyflavanone, in Cultured Glycyrrhiza echinata L. Cells. | Otani K, Takahashi T, Furuya T, Ayabe S | 1994 Aug | 12232298 |