Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.144
Description:Abieta-7,13-diene hydroxylase.
Alternative Name: Abietadiene hydroxylase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.144
BRENDA Enzyme Link: BRENDA 1.14.14.144
KEGG Enzyme Link: KEGG1.14.14.144
BioCyc Enzyme Link: BioCyc 1.14.14.144
ExPASy Enzyme Link: ExPASy1.14.14.144
EC2PDB Enzyme Link: EC2PDB 1.14.14.144
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.144
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.144
IntEnz Enzyme Link: IntEnz 1.14.14.144
MEDLINE Enzyme Link: MEDLINE 1.14.14.144
MSA:

1.14.14.144;

Phylogenetic Tree:

1.14.14.144;

Uniprot:
M-CSA:
RHEA:26217 abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase] = abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH;+0:9]=[CH;+0:10]-1.[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[CH2;+0:2]-[OH;+0:12].[*:3]-[n+;H0:4]1:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:1.[OH2;+0:13]
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References

TitleAuthorsDatePubMed ID
Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis.Funk C, Croteau R1994 Jan8311462
Regulation of Oleoresinosis in Grand Fir (Abies grandis) (Coordinate Induction of Monoterpene and Diterpene Cyclases and Two Cytochrome P450-Dependent Diterpenoid Hydroxylases by Stem Wounding).Funk C, Lewinsohn E, Vogel BS, Steele CL, Croteau R1994 Nov12232380