| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.144 |
|---|---|
| Description: | Abieta-7,13-diene hydroxylase. |
| Alternative Name: |
Abietadiene hydroxylase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.14.144 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.144 |
| KEGG Enzyme Link: | KEGG1.14.14.144 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.144 |
| ExPASy Enzyme Link: | ExPASy1.14.14.144 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.144 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.144 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.144 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.144 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.144 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:26217 | abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase] = abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH3;+0:2].[*:3]-[N;H0;+0:4]1-[CH;+0:5]=[C;H0;+0:6](-[*:7])-[CH2;+0:8]-[CH;+0:9]=[CH;+0:10]-1.[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[*:1]-[CH2;+0:2]-[OH;+0:12].[*:3]-[n+;H0:4]1:[cH;+0:5]:[c;H0;+0:6](-[*:7]):[cH;+0:8]:[cH;+0:9]:[cH;+0:10]:1.[OH2;+0:13] |
| Reaction | ![]() |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis. | Funk C, Croteau R | 1994 Jan | 8311462 |
| Regulation of Oleoresinosis in Grand Fir (Abies grandis) (Coordinate Induction of Monoterpene and Diterpene Cyclases and Two Cytochrome P450-Dependent Diterpenoid Hydroxylases by Stem Wounding). | Funk C, Lewinsohn E, Vogel BS, Steele CL, Croteau R | 1994 Nov | 12232380 |