Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.147
Description:3-epi-6-deoxocathasterone 23-monooxygenase.
Alternative Name: CYP90D1.
CYP90C1.
Prosite: PDOC00081;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.147
BRENDA Enzyme Link: BRENDA 1.14.14.147
KEGG Enzyme Link: KEGG1.14.14.147
BioCyc Enzyme Link: BioCyc 1.14.14.147
ExPASy Enzyme Link: ExPASy1.14.14.147
EC2PDB Enzyme Link: EC2PDB 1.14.14.147
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.147
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.147
IntEnz Enzyme Link: IntEnz 1.14.14.147
MEDLINE Enzyme Link: MEDLINE 1.14.14.147
MSA:

1.14.14.147;

Phylogenetic Tree:

1.14.14.147;

Uniprot:
M-CSA:
RHEA:27325 (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydro-6-deoxoteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH2;+0:9]-[CH;+0:10]=[CH;+0:11]-1.[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:13].[*:4]-[n+;H0:5]1:[cH;+0:6]:[c;H0;+0:7](-[*:8]):[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:1.[OH2;+0:14]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis.Ohnishi T, Szatmari AM, Watanabe B, Fujita S, Bancos S, Koncz C, Lafos M, Shibata K, Yokota T, Sakata K, Szekeres M, Mizutani M2006 Nov17138693

RHEA:27321 3-epi-6-deoxocathasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6-deoxotyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH2;+0:9]-[CH;+0:10]=[CH;+0:11]-1.[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:13].[*:4]-[n+;H0:5]1:[cH;+0:6]:[c;H0;+0:7](-[*:8]):[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:1.[OH2;+0:14]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
C-23 hydroxylation by Arabidopsis CYP90C1 and CYP90D1 reveals a novel shortcut in brassinosteroid biosynthesis.Ohnishi T, Szatmari AM, Watanabe B, Fujita S, Bancos S, Koncz C, Lafos M, Shibata K, Yokota T, Sakata K, Szekeres M, Mizutani M2006 Nov17138693