Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.148
Description:Angelicin synthase.
Alternative Name: CYP71AJ4.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.148
BRENDA Enzyme Link: BRENDA 1.14.14.148
KEGG Enzyme Link: KEGG1.14.14.148
BioCyc Enzyme Link: BioCyc 1.14.14.148
ExPASy Enzyme Link: ExPASy1.14.14.148
EC2PDB Enzyme Link: EC2PDB 1.14.14.148
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.148
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.148
IntEnz Enzyme Link: IntEnz 1.14.14.148
MEDLINE Enzyme Link: MEDLINE 1.14.14.148
MSA:

1.14.14.148;

Phylogenetic Tree:

1.14.14.148;

Uniprot:
M-CSA:
RHEA:27481 (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase] = acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])(-[OH;+0:4])-[CH;+0:5]1-[CH2;+0:6]-[*:7]:[*:8]-[O;H0;+0:9]-1.[*:10]-[N;H0;+0:11]1-[CH;+0:12]=[C;H0;+0:13](-[*:14])-[CH2;+0:15]-[CH;+0:16]=[CH;+0:17]-1.[H+;H0:18].[O;H0;+0:19]=[O;H0;+0:20]>>[*:1]-[C;H0;+0:2](-[*:3])=[O;H0;+0:4].[*:10]-[n+;H0:11]1:[cH;+0:12]:[c;H0;+0:13](-[*:14]):[cH;+0:15]:[cH;+0:16]:[cH;+0:17]:1.[*:8]1:[*:7]:[cH;+0:6]:[cH;+0:5]:[o;H0;+0:9]:1.[OH2;+0:19].[OH2;+0:20]
Reaction
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References

TitleAuthorsDatePubMed ID
Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis.Larbat R, Hehn A, Hans J, Schneider S, Jugdé H, Schneider B, Matern U, Bourgaud F2009 Feb 2019098286