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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

ID:	1.14.14.15
Description:	protein SgcC2] monooxygenase.

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UniProtKB Enzyme Link:	UniProtKB 1.14.14.15
BRENDA Enzyme Link:	BRENDA 1.14.14.15
KEGG Enzyme Link:	KEGG1.14.14.15
BioCyc Enzyme Link:	BioCyc 1.14.14.15
ExPASy Enzyme Link:	ExPASy1.14.14.15
EC2PDB Enzyme Link:	EC2PDB 1.14.14.15
ExplorEnz Enzyme Link:	ExplorEnz 1.14.14.15
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.14.15
IntEnz Enzyme Link:	IntEnz 1.14.14.15
MEDLINE Enzyme Link:	MEDLINE 1.14.14.15

RHEA:41560	(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2 = (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H(+) + H2O
RULE(radius=1)	[:1]-[N;H0;+0:2]1-[:3]:[:4]-[NH;+0:5]-[c;H0;+0:6](:[:7]):[c;H0;+0:8]-1:[nH;+0:9]:[:10].[:11]:[cH;+0:12]:[:13].[O;H0;+0:14]=[O;H0;+0:15]>>[:1]-[n;H0;+0:2]1:[:3]:[:4]:[n;H0;+0:5]:[c;H0;+0:6](:[:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[:10].[:11]:[c;H0;+0:12](:[:13])-[OH;+0:14].[OH2;+0:15]
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Title	Authors	Date	PubMed ID
Characterization of the two-component, FAD-dependent monooxygenase SgcC that requires carrier protein-tethered substrates for the biosynthesis of the enediyne antitumor antibiotic C-1027.	Lin S, Van Lanen SG, Shen B	2008 May 21	18426211