EC number:1.14.14.151
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.151 | ||
|---|---|---|---|
| Description: | Premnaspirodiene oxygenase. | ||
| Alternative Name: |
Hyoscymus muticus premnaspirodiene oxygenase. HPO. CYP71D55. | ||
| Prosite: | PDOC00081; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.151 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.151 |
| KEGG Enzyme Link: | KEGG1.14.14.151 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.151 |
| ExPASy Enzyme Link: | ExPASy1.14.14.151 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.151 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.151 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.151 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.151 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.151 |
EC number:1.14.14.151
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:32455 | (-)-vetispiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + solavetivone |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[N;H0;+0:4](-[*:5])-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-1.[*:9]-[CH2;+0:10]-[*:11].[*:12]-[N;H0;+0:13]1-[CH;+0:14]=[C;H0;+0:15](-[*:16])-[CH2;+0:17]-[CH;+0:18]=[CH;+0:19]-1.[H+;H0:20].[H+;H0:21].[O;H0;+0:22]=[O;H0;+0:23].[O;H0;+0:24]=[O;H0;+0:25]>>[*:9]-[C;H0;+0:10](-[*:11])=[O;H0;+0:22].[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[n+;H0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:12]-[n+;H0:13]1:[cH;+0:14]:[c;H0;+0:15](-[*:16]):[cH;+0:17]:[cH;+0:18]:[cH;+0:19]:1.[OH2;+0:23].[OH2;+0:24].[OH2;+0:25] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates. | Takahashi S, Yeo YS, Zhao Y, O'Maille PE, Greenhagen BT, Noel JP, Coates RM, Chappell J | 2007 Oct 26 | 17715131 |