| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.153 |
|---|---|
| Description: | Indole-2-monooxygenase. |
| Alternative Name: |
CYP71C4. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 1.14.14.153 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.153 |
| KEGG Enzyme Link: | KEGG1.14.14.153 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.153 |
| ExPASy Enzyme Link: | ExPASy1.14.14.153 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.153 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.153 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.153 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.153 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.153 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:31899 | indole + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]1:[*:10]:[cH;+0:11]:[cH;+0:12]:[nH;+0:13]:1.[H+;H0:14].[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[O;H0;+0:15]=[C;H0;+0:12]1-[CH2;+0:11]-[*:10]:[*:9]-[NH;+0:13]-1.[OH2;+0:16] |
| Reaction | ![]() |
| Core-to-Core | |
| Core-to-Core |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Analysis of a chemical plant defense mechanism in grasses. | Frey M, Chomet P, Glawischnig E, Stettner C, Grün S, Winklmair A, Eisenreich W, Bacher A, Meeley RB, Briggs SP, Simcox K, Gierl A | 1997 Aug 1 | 9235894 |
| Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses. | Glawischnig E, Grün S, Frey M, Gierl A | 1999 Mar | 10385992 |