EC number:1.14.14.35

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.35
Description:Dimethylsulfone monooxygenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.35
BRENDA Enzyme Link: BRENDA 1.14.14.35
KEGG Enzyme Link: KEGG1.14.14.35
BioCyc Enzyme Link: BioCyc 1.14.14.35
ExPASy Enzyme Link: ExPASy1.14.14.35
EC2PDB Enzyme Link: EC2PDB 1.14.14.35
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.35
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.35
IntEnz Enzyme Link: IntEnz 1.14.14.35
MEDLINE Enzyme Link: MEDLINE 1.14.14.35

EC number:1.14.14.35

MSA:

1.14.14.35;
Phylogenetic Tree:

1.14.14.35;
Uniprot:
M-CSA:
RHEA:50720 FMNH2 + methanesulfinate + O2 = FMN + H(+) + H2O + methanesulfonate
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]=[S;H0;+0:12](-[*:13])-[*:14].[O;H0;+0:15]=[O;H0;+0:16]>>[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]=[S;H0;+0:12](-[*:13])(-[*:14])=[O;H0;+0:15].[OH2;+0:16]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate.Wicht DK2016 Aug 1527392454
RHEA:50716 dimethyl sulfone + FMNH2 + O2 = FMN + formaldehyde + 2 H(+) + H2O + methanesulfinate
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]=[S;H0;+0:12](-[*:13])(-[CH3;+0:14])=[O;H0;+0:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]=[S;H0;+0:12](-[*:13])-[OH;+0:15].[CH2;+0:14]=[O;H0;+0:16].[OH2;+0:17]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate.Wicht DK2016 Aug 1527392454
The sigma54-dependent transcriptional activator SfnR regulates the expression of the Pseudomonas putida sfnFG operon responsible for dimethyl sulphone utilization.Endoh T, Habe H, Nojiri H, Yamane H, Omori T2005 Feb15661012