EC number:1.14.14.40
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.40 |
|---|---|
| Description: | Phenylalanine N-monooxygenase. |
| Alternative Name: |
Phenylalanine N-hydroxylase. CYP79D16. CYP79A2. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.40 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.40 |
| KEGG Enzyme Link: | KEGG1.14.14.40 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.40 |
| ExPASy Enzyme Link: | ExPASy1.14.14.40 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.40 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.40 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.40 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.40 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.40 |
EC number:1.14.14.40
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:33263 | L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[N;H0;+0:4](-[*:5])-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-1.[*:9]-[CH;+0:10](-[NH2;+0:11])-[C;H0;+0:12](=[*:13])-[OH;+0:14].[*:15]-[N;H0;+0:16]1-[CH;+0:17]=[C;H0;+0:18](-[*:19])-[CH2;+0:20]-[CH;+0:21]=[CH;+0:22]-1.[O;H0;+0:23]=[O;H0;+0:24].[O;H0;+0:25]=[O;H0;+0:26]>>[*:9]-[CH;+0:10]=[N;H0;+0:11]-[OH;+0:23].[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[n+;H0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:15]-[n+;H0:16]1:[cH;+0:17]:[c;H0;+0:18](-[*:19]):[cH;+0:20]:[cH;+0:21]:[cH;+0:22]:1.[*:13]=[C;H0;+0:12]=[O;H0;+0:14].[OH2;+0:24].[OH2;+0:25].[OH2;+0:26] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification and characterization of CYP79D16 and CYP71AN24 catalyzing the first and second steps in L-phenylalanine-derived cyanogenic glycoside biosynthesis in the Japanese apricot, Prunus mume Sieb. et Zucc. | Yamaguchi T, Yamamoto K, Asano Y | 2014 Sep | 25015725 |
| Cytochrome P450 CYP79A2 from Arabidopsis thaliana L. Catalyzes the conversion of L-phenylalanine to phenylacetaldoxime in the biosynthesis of benzylglucosinolate. | Wittstock U, Halkier BA | 2000 May 12 | 10799553 |