EC number:1.14.14.42

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.42
Description:Homomethionine N-monooxygenase.
Alternative Name: CYP79F1.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.42
BRENDA Enzyme Link: BRENDA 1.14.14.42
KEGG Enzyme Link: KEGG1.14.14.42
BioCyc Enzyme Link: BioCyc 1.14.14.42
ExPASy Enzyme Link: ExPASy1.14.14.42
EC2PDB Enzyme Link: EC2PDB 1.14.14.42
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.42
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.42
IntEnz Enzyme Link: IntEnz 1.14.14.42
MEDLINE Enzyme Link: MEDLINE 1.14.14.42

EC number:1.14.14.42

MSA:

1.14.14.42;
Phylogenetic Tree:

1.14.14.42;
Uniprot:
M-CSA:
RHEA:32719 L-dihomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-5-(methylsulfanyl)pentanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]:[nH;+0:12]:[c;H0;+0:13]1:[c;H0;+0:14](:[*:15])-[NH;+0:16]-[*:17]:[*:18]-[N;H0;+0:19]-1-[*:20].[*:21]=[C;H0;+0:22](-[OH;+0:23])-[CH;+0:24](-[*:25])-[NH2;+0:26].[O;H0;+0:27]=[O;H0;+0:28].[O;H0;+0:29]=[O;H0;+0:30]>>[*:25]-[CH;+0:24]=[N;H0;+0:26]-[OH;+0:27].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]:[n;H0;+0:12]:[c;H0;+0:13]1:[n;H0;+0:19](-[*:20]):[*:18]:[*:17]:[n;H0;+0:16]:[c;H0;+0:14]-1:[*:15].[*:21]=[C;H0;+0:22]=[O;H0;+0:23].[OH2;+0:28].[OH2;+0:29].[OH2;+0:30]
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References

TitleAuthorsDatePubMed ID
CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA2003 Mar12609033
Cytochrome p450 CYP79F1 from arabidopsis catalyzes the conversion of dihomomethionine and trihomomethionine to the corresponding aldoximes in the biosynthesis of aliphatic glucosinolates.Hansen CH, Wittstock U, Olsen CE, Hick AJ, Pickett JA, Halkier BA2001 Apr 611133994
RHEA:32723 L-trihomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-6-(methylsulfanyl)hexanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]:[nH;+0:12]:[c;H0;+0:13]1:[c;H0;+0:14](:[*:15])-[NH;+0:16]-[*:17]:[*:18]-[N;H0;+0:19]-1-[*:20].[*:21]=[C;H0;+0:22](-[OH;+0:23])-[CH;+0:24](-[*:25])-[NH2;+0:26].[O;H0;+0:27]=[O;H0;+0:28].[O;H0;+0:29]=[O;H0;+0:30]>>[*:25]-[CH;+0:24]=[N;H0;+0:26]-[OH;+0:27].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]:[n;H0;+0:12]:[c;H0;+0:13]1:[n;H0;+0:19](-[*:20]):[*:18]:[*:17]:[n;H0;+0:16]:[c;H0;+0:14]-1:[*:15].[*:21]=[C;H0;+0:22]=[O;H0;+0:23].[OH2;+0:28].[OH2;+0:29].[OH2;+0:30]
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References

TitleAuthorsDatePubMed ID
CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA2003 Mar12609033
Cytochrome p450 CYP79F1 from arabidopsis catalyzes the conversion of dihomomethionine and trihomomethionine to the corresponding aldoximes in the biosynthesis of aliphatic glucosinolates.Hansen CH, Wittstock U, Olsen CE, Hick AJ, Pickett JA, Halkier BA2001 Apr 611133994
RHEA:33243 L-tetrahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]:[nH;+0:12]:[c;H0;+0:13]1:[c;H0;+0:14](:[*:15])-[NH;+0:16]-[*:17]:[*:18]-[N;H0;+0:19]-1-[*:20].[*:21]=[C;H0;+0:22](-[OH;+0:23])-[CH;+0:24](-[*:25])-[NH2;+0:26].[O;H0;+0:27]=[O;H0;+0:28].[O;H0;+0:29]=[O;H0;+0:30]>>[*:25]-[CH;+0:24]=[N;H0;+0:26]-[OH;+0:27].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]:[n;H0;+0:12]:[c;H0;+0:13]1:[n;H0;+0:19](-[*:20]):[*:18]:[*:17]:[n;H0;+0:16]:[c;H0;+0:14]-1:[*:15].[*:21]=[C;H0;+0:22]=[O;H0;+0:23].[OH2;+0:28].[OH2;+0:29].[OH2;+0:30]
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References

TitleAuthorsDatePubMed ID
CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA2003 Mar12609033
Cytochrome p450 CYP79F1 from arabidopsis catalyzes the conversion of dihomomethionine and trihomomethionine to the corresponding aldoximes in the biosynthesis of aliphatic glucosinolates.Hansen CH, Wittstock U, Olsen CE, Hick AJ, Pickett JA, Halkier BA2001 Apr 611133994
RHEA:33291 L-pentahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-8-(methylsulfanyl)octanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]:[nH;+0:12]:[c;H0;+0:13]1:[c;H0;+0:14](:[*:15])-[NH;+0:16]-[*:17]:[*:18]-[N;H0;+0:19]-1-[*:20].[*:21]=[C;H0;+0:22](-[OH;+0:23])-[CH;+0:24](-[*:25])-[NH2;+0:26].[H+;H0:27].[H+;H0:28].[O;H0;+0:29]=[O;H0;+0:30].[O;H0;+0:31]=[O;H0;+0:32]>>[*:25]-[CH;+0:24]=[N;H0;+0:26]-[OH;+0:29].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]:[n;H0;+0:12]:[c;H0;+0:13]1:[n;H0;+0:19](-[*:20]):[*:18]:[*:17]:[n;H0;+0:16]:[c;H0;+0:14]-1:[*:15].[*:21]=[C;H0;+0:22]=[O;H0;+0:23].[OH2;+0:30].[OH2;+0:31].[OH2;+0:32]
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References

TitleAuthorsDatePubMed ID
CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA2003 Mar12609033
Cytochrome p450 CYP79F1 from arabidopsis catalyzes the conversion of dihomomethionine and trihomomethionine to the corresponding aldoximes in the biosynthesis of aliphatic glucosinolates.Hansen CH, Wittstock U, Olsen CE, Hick AJ, Pickett JA, Halkier BA2001 Apr 611133994
RHEA:33295 L-hexahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-9-(methylsulfanyl)nonanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]:[nH;+0:12]:[c;H0;+0:13]1:[c;H0;+0:14](:[*:15])-[NH;+0:16]-[*:17]:[*:18]-[N;H0;+0:19]-1-[*:20].[*:21]=[C;H0;+0:22](-[OH;+0:23])-[CH;+0:24](-[*:25])-[NH2;+0:26].[O;H0;+0:27]=[O;H0;+0:28].[O;H0;+0:29]=[O;H0;+0:30]>>[*:25]-[CH;+0:24]=[N;H0;+0:26]-[OH;+0:27].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]:[n;H0;+0:12]:[c;H0;+0:13]1:[n;H0;+0:19](-[*:20]):[*:18]:[*:17]:[n;H0;+0:16]:[c;H0;+0:14]-1:[*:15].[*:21]=[C;H0;+0:22]=[O;H0;+0:23].[OH2;+0:28].[OH2;+0:29].[OH2;+0:30]
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References

TitleAuthorsDatePubMed ID
CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA2003 Mar12609033
RHEA:51972 an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[N;H0;+0:4](-[*:5])-[CH;+0:6]=[CH;+0:7]-[CH2;+0:8]-1.[*:9]-[CH;+0:10](-[NH2;+0:11])-[C;H0;+0:12](=[*:13])-[OH;+0:14].[*:15]-[N;H0;+0:16]1-[CH;+0:17]=[C;H0;+0:18](-[*:19])-[CH2;+0:20]-[CH;+0:21]=[CH;+0:22]-1.[O;H0;+0:23]=[O;H0;+0:24].[O;H0;+0:25]=[O;H0;+0:26]>>[*:9]-[CH;+0:10]=[N;H0;+0:11]-[OH;+0:23].[*:1]-[c;H0;+0:2]1:[cH;+0:3]:[n+;H0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:15]-[n+;H0:16]1:[cH;+0:17]:[c;H0;+0:18](-[*:19]):[cH;+0:20]:[cH;+0:21]:[cH;+0:22]:1.[*:13]=[C;H0;+0:12]=[O;H0;+0:14].[OH2;+0:24].[OH2;+0:25].[OH2;+0:26]
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References

TitleAuthorsDatePubMed ID
CYP79F1 and CYP79F2 have distinct functions in the biosynthesis of aliphatic glucosinolates in Arabidopsis.Chen S, Glawischnig E, Jørgensen K, Naur P, Jørgensen B, Olsen CE, Hansen CH, Rasmussen H, Pickett JA, Halkier BA2003 Mar12609033
Cytochrome p450 CYP79F1 from arabidopsis catalyzes the conversion of dihomomethionine and trihomomethionine to the corresponding aldoximes in the biosynthesis of aliphatic glucosinolates.Hansen CH, Wittstock U, Olsen CE, Hick AJ, Pickett JA, Halkier BA2001 Apr 611133994