EC Tree |
1. Oxidoreductases |
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
ID: | 1.14.14.45 |
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Description: | Aromatic aldoxime N-monooxygenase. |
Alternative Name: |
CYP83B1. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.14.14.45 |
BRENDA Enzyme Link: | BRENDA 1.14.14.45 |
KEGG Enzyme Link: | KEGG1.14.14.45 |
BioCyc Enzyme Link: | BioCyc 1.14.14.45 |
ExPASy Enzyme Link: | ExPASy1.14.14.45 |
EC2PDB Enzyme Link: | EC2PDB 1.14.14.45 |
ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.45 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.45 |
IntEnz Enzyme Link: | IntEnz 1.14.14.45 |
MEDLINE Enzyme Link: | MEDLINE 1.14.14.45 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:52192 | (E)-phenylacetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] |
RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]-[SH;+0:12].[*:13]=[CH;+0:14]-[*:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:11]-[S;H0;+0:12]-[C;H0;+0:14](=[*:13])-[*:15].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[OH2;+0:16].[OH2;+0:17] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis. | Naur P, Petersen BL, Mikkelsen MD, Bak S, Rasmussen H, Olsen CE, Halkier BA | 2003 Sep | 12970475 |
CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis. | Bak S, Tax FE, Feldmann KA, Galbraith DW, Feyereisen R | 2001 Jan | 11158532 |
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis. | Geu-Flores F, Møldrup ME, Böttcher C, Olsen CE, Scheel D, Halkier BA | 2011 Jun | 21712415 |
RHEA:52180 | (E)-(indol-3-yl)acetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] |
RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]-[SH;+0:12].[*:13]=[CH;+0:14]-[*:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:11]-[S;H0;+0:12]-[C;H0;+0:14](=[*:13])-[*:15].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[OH2;+0:16].[OH2;+0:17] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
---|---|---|---|
CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis. | Naur P, Petersen BL, Mikkelsen MD, Bak S, Rasmussen H, Olsen CE, Halkier BA | 2003 Sep | 12970475 |
CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis. | Bak S, Tax FE, Feldmann KA, Galbraith DW, Feyereisen R | 2001 Jan | 11158532 |
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis. | Geu-Flores F, Møldrup ME, Böttcher C, Olsen CE, Scheel D, Halkier BA | 2011 Jun | 21712415 |