Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.45
Description:Aromatic aldoxime N-monooxygenase.
Alternative Name: CYP83B1.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.45
BRENDA Enzyme Link: BRENDA 1.14.14.45
KEGG Enzyme Link: KEGG1.14.14.45
BioCyc Enzyme Link: BioCyc 1.14.14.45
ExPASy Enzyme Link: ExPASy1.14.14.45
EC2PDB Enzyme Link: EC2PDB 1.14.14.45
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.45
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.45
IntEnz Enzyme Link: IntEnz 1.14.14.45
MEDLINE Enzyme Link: MEDLINE 1.14.14.45
MSA:

1.14.14.45;

Phylogenetic Tree:

1.14.14.45;

Uniprot:
M-CSA:
RHEA:52192 (E)-phenylacetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]-[SH;+0:12].[*:13]=[CH;+0:14]-[*:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:11]-[S;H0;+0:12]-[C;H0;+0:14](=[*:13])-[*:15].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[OH2;+0:16].[OH2;+0:17]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis.Naur P, Petersen BL, Mikkelsen MD, Bak S, Rasmussen H, Olsen CE, Halkier BA2003 Sep12970475
CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis.Bak S, Tax FE, Feldmann KA, Galbraith DW, Feyereisen R2001 Jan11158532
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis.Geu-Flores F, Møldrup ME, Böttcher C, Olsen CE, Scheel D, Halkier BA2011 Jun21712415

RHEA:52180 (E)-(indol-3-yl)acetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] = (E)-1-(glutathione-S-yl)-2-(1H-indol-3-yl)acetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]-[SH;+0:12].[*:13]=[CH;+0:14]-[*:15].[O;H0;+0:16]=[O;H0;+0:17]>>[*:11]-[S;H0;+0:12]-[C;H0;+0:14](=[*:13])-[*:15].[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[OH2;+0:16].[OH2;+0:17]
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis.Naur P, Petersen BL, Mikkelsen MD, Bak S, Rasmussen H, Olsen CE, Halkier BA2003 Sep12970475
CYP83B1, a cytochrome P450 at the metabolic branch point in auxin and indole glucosinolate biosynthesis in Arabidopsis.Bak S, Tax FE, Feldmann KA, Galbraith DW, Feyereisen R2001 Jan11158532
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis.Geu-Flores F, Møldrup ME, Böttcher C, Olsen CE, Scheel D, Halkier BA2011 Jun21712415