EC number:1.14.14.46
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.46 |
|---|---|
| Description: | Pimeloyl-[acyl-carrier protein] synthase. |
| Alternative Name: |
CYP107H1. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.46 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.46 |
| KEGG Enzyme Link: | KEGG1.14.14.46 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.46 |
| ExPASy Enzyme Link: | ExPASy1.14.14.46 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.46 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.46 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.46 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.46 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.46 |
EC number:1.14.14.46
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:52852 | a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] = a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin] + pimeloyl-[ACP] |
| RULE(radius=1) | ([*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[CH;+0:6](-[*:7])-[C;H0;+0:8](-[*:9])=[*:10]).[*:11]:[nH;+0:12]:[c;H0;+0:13]1:[c;H0;+0:14](:[*:15])-[NH;+0:16]-[*:17]:[*:18]-[N;H0;+0:19]-1-[*:20].[*:21]:[nH;+0:22]:[c;H0;+0:23]1:[c;H0;+0:24](:[*:25])-[NH;+0:26]-[*:27]:[*:28]-[N;H0;+0:29]-1-[*:30].[O;H0;+0:31]=[O;H0;+0:32].[O;H0;+0:33]=[O;H0;+0:34].[O;H0;+0:35]=[O;H0;+0:36]>>([*:1]-[C;H0;+0:2](=[O;H0;+0:35])-[OH;+0:36].[*:5]-[CH;+0:6](-[*:7])-[C;H0;+0:3](-[*:4])=[O;H0;+0:34]).[*:9]-[CH;+0:8]=[*:10].[*:11]:[n;H0;+0:12]:[c;H0;+0:13]1:[n;H0;+0:19](-[*:20]):[*:18]:[*:17]:[n;H0;+0:16]:[c;H0;+0:14]-1:[*:15].[*:21]:[n;H0;+0:22]:[c;H0;+0:23]1:[n;H0;+0:29](-[*:30]):[*:28]:[*:27]:[n;H0;+0:26]:[c;H0;+0:24]-1:[*:25].[OH2;+0:31].[OH2;+0:32].[OH2;+0:33] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Selectivity in a barren landscape: the P450(BioI)-ACP complex. | Cryle MJ | 2010 Aug | 20658980 |
| Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. | Cryle MJ, Schlichting I | 2008 Oct 14 | 18838690 |
| Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1). | Cryle MJ, De Voss JJ | 2004 Jan 7 | 14737344 |
| Expression, purification, and characterization of BioI: a carbon-carbon bond cleaving cytochrome P450 involved in biotin biosynthesis in Bacillus subtilis. | Stok JE, De Voss J | 2000 Dec 15 | 11368323 |