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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

ID:	1.14.14.49
Description:	12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase.
Alternative Name:	CYP94C1.

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UniProtKB Enzyme Link:	UniProtKB 1.14.14.49
BRENDA Enzyme Link:	BRENDA 1.14.14.49
KEGG Enzyme Link:	KEGG1.14.14.49
BioCyc Enzyme Link:	BioCyc 1.14.14.49
ExPASy Enzyme Link:	ExPASy1.14.14.49
EC2PDB Enzyme Link:	EC2PDB 1.14.14.49
ExplorEnz Enzyme Link:	ExplorEnz 1.14.14.49
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.14.49
IntEnz Enzyme Link:	IntEnz 1.14.14.49
MEDLINE Enzyme Link:	MEDLINE 1.14.14.49

RHEA:55056	a 12-hydroxyjasmonyl-L-alpha-amino acid + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = a 12-hydroxy-12-oxojasmonyl-L-alpha-amino acid + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1)	[:1]-[CH2;+0:2]-[:3].[:4]-[N;H0;+0:5]1-[:6]:[:7]-[NH;+0:8]-[c;H0;+0:9](:[:10]):[c;H0;+0:11]-1:[nH;+0:12]:[:13].[:14]:[nH;+0:15]:[c;H0;+0:16]1:[c;H0;+0:17](:[:18])-[NH;+0:19]-[:20]:[:21]-[N;H0;+0:22]-1-[:23].[O;H0;+0:24]=[O;H0;+0:25].[O;H0;+0:26]=[O;H0;+0:27]>>[:1]-[C;H0;+0:2](-[:3])=[O;H0;+0:24].[:4]-[n;H0;+0:5]1:[:6]:[:7]:[n;H0;+0:8]:[c;H0;+0:9](:[:10])-[c;H0;+0:11]:1:[n;H0;+0:12]:[:13].[:14]:[n;H0;+0:15]:[c;H0;+0:16]1:[n;H0;+0:22](-[:23]):[:21]:[:20]:[n;H0;+0:19]:[c;H0;+0:17]-1:[:18].[OH2;+0:25].[OH2;+0:26].[OH2;+0:27]
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Title	Authors	Date	PubMed ID
Functional Characterization of CYP94-Genes and Identification of a Novel Jasmonate Catabolite in Flowers.	Bruckhoff V, Haroth S, Feussner K, König S, Brodhun F, Feussner I	2016	27459369
Sequential oxidation of Jasmonoyl-Phenylalanine and Jasmonoyl-Isoleucine by multiple cytochrome P450 of the CYP94 family through newly identified aldehyde intermediates.	Widemann E, Grausem B, Renault H, Pineau E, Heinrich C, Lugan R, Ullmann P, Miesch L, Aubert Y, Miesch M, Heitz T, Pinot F	2015 Sep	26164240
Cytochromes P450 CYP94C1 and CYP94B3 catalyze two successive oxidation steps of plant hormone Jasmonoyl-isoleucine for catabolic turnover.	Heitz T, Widemann E, Lugan R, Miesch L, Ullmann P, Désaubry L, Holder E, Grausem B, Kandel S, Miesch M, Werck-Reichhart D, Pinot F	2012 Feb 24	22215670