EC number:1.14.14.54

Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.54
Description:Phenylacetate 2-hydroxylase.
Alternative Name: CYP504.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.54
BRENDA Enzyme Link: BRENDA 1.14.14.54
KEGG Enzyme Link: KEGG1.14.14.54
BioCyc Enzyme Link: BioCyc 1.14.14.54
ExPASy Enzyme Link: ExPASy1.14.14.54
EC2PDB Enzyme Link: EC2PDB 1.14.14.54
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.54
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.54
IntEnz Enzyme Link: IntEnz 1.14.14.54
MEDLINE Enzyme Link: MEDLINE 1.14.14.54

EC number:1.14.14.54

MSA:

1.14.14.54;
Phylogenetic Tree:

1.14.14.54;
Uniprot:
M-CSA:
RHEA:53392 2-phenylacetate + O2 + reduced [NADPH--hemoprotein reductase] = (2-hydroxyphenyl)acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]:[*:4]-[NH;+0:5]-[c;H0;+0:6](:[*:7]):[c;H0;+0:8]-1:[nH;+0:9]:[*:10].[*:11]:[cH;+0:12]:[*:13].[O;H0;+0:14]=[O;H0;+0:15]>>[*:1]-[n;H0;+0:2]1:[*:3]:[*:4]:[n;H0;+0:5]:[c;H0;+0:6](:[*:7])-[c;H0;+0:8]:1:[n;H0;+0:9]:[*:10].[*:11]:[c;H0;+0:12](:[*:13])-[OH;+0:14].[OH2;+0:15]
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References

TitleAuthorsDatePubMed ID
Disruption of phacA, an Aspergillus nidulans gene encoding a novel cytochrome P450 monooxygenase catalyzing phenylacetate 2-hydroxylation, results in penicillin overproduction.Mingot JM, Peñalva MA, Fernández-Cañón JM1999 May 2110329644