EC number:1.14.14.63
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.63 |
|---|---|
| Description: | Beta-amyrin 16-beta-monooxygenase. |
| Alternative Name: |
CYP716A141. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.63 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.63 |
| KEGG Enzyme Link: | KEGG1.14.14.63 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.63 |
| ExPASy Enzyme Link: | ExPASy1.14.14.63 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.63 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.63 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.63 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.63 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.63 |
EC number:1.14.14.63
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:55444 | O2 + oleanolate + reduced [NADPH--hemoprotein reductase] = cochalate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]:[nH;+0:5]:[c;H0;+0:6]1:[c;H0;+0:7](:[*:8])-[NH;+0:9]-[*:10]:[*:11]-[N;H0;+0:12]-1-[*:13].[O;H0;+0:14]=[O;H0;+0:15]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:14].[*:4]:[n;H0;+0:5]:[c;H0;+0:6]1:[n;H0;+0:12](-[*:13]):[*:11]:[*:10]:[n;H0;+0:9]:[c;H0;+0:7]-1:[*:8].[OH2;+0:15] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cytochrome P450 Monooxygenase CYP716A141 is a Unique β-Amyrin C-16β Oxidase Involved in Triterpenoid Saponin Biosynthesis in Platycodon grandiflorus. | Tamura K, Teranishi Y, Ueda S, Suzuki H, Kawano N, Yoshimatsu K, Saito K, Kawahara N, Muranaka T, Seki H | 2017 May 1 | 28371833 |
| RHEA:55440 | beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + maniladiol + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[*:6]:[*:7]-[NH;+0:8]-[c;H0;+0:9](:[*:10]):[c;H0;+0:11]-1:[nH;+0:12]:[*:13].[O;H0;+0:14]=[O;H0;+0:15]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:14].[*:4]-[n;H0;+0:5]1:[*:6]:[*:7]:[n;H0;+0:8]:[c;H0;+0:9](:[*:10])-[c;H0;+0:11]:1:[n;H0;+0:12]:[*:13].[OH2;+0:15] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cytochrome P450 Monooxygenase CYP716A141 is a Unique β-Amyrin C-16β Oxidase Involved in Triterpenoid Saponin Biosynthesis in Platycodon grandiflorus. | Tamura K, Teranishi Y, Ueda S, Suzuki H, Kawano N, Yoshimatsu K, Saito K, Kawahara N, Muranaka T, Seki H | 2017 May 1 | 28371833 |