Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.68
Description:Syn-pimaradiene 3-monooxygenase.
Alternative Name: CYP701A8.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.68
BRENDA Enzyme Link: BRENDA 1.14.14.68
KEGG Enzyme Link: KEGG1.14.14.68
BioCyc Enzyme Link: BioCyc 1.14.14.68
ExPASy Enzyme Link: ExPASy1.14.14.68
EC2PDB Enzyme Link: EC2PDB 1.14.14.68
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.68
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.68
IntEnz Enzyme Link: IntEnz 1.14.14.68
MEDLINE Enzyme Link: MEDLINE 1.14.14.68
MSA:

1.14.14.68;

Phylogenetic Tree:

1.14.14.68;

Uniprot:
M-CSA:
RHEA:55472 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-diene-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[*:6]:[*:7]-[NH;+0:8]-[c;H0;+0:9](:[*:10]):[c;H0;+0:11]-1:[nH;+0:12]:[*:13].[O;H0;+0:14]=[O;H0;+0:15]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:14].[*:4]-[n;H0;+0:5]1:[*:6]:[*:7]:[n;H0;+0:8]:[c;H0;+0:9](:[*:10])-[c;H0;+0:11]:1:[n;H0;+0:12]:[*:13].[OH2;+0:15]
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References

TitleAuthorsDatePubMed ID
Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis.Kitaoka N, Wu Y, Xu M, Peters RJ2015 Sep25758958
Characterization of CYP76M5-8 indicates metabolic plasticity within a plant biosynthetic gene cluster.Wang Q, Hillwig ML, Okada K, Yamazaki K, Wu Y, Swaminathan S, Yamane H, Peters RJ2012 Feb 2422215681