EC number:1.14.14.70

Enzyme

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     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.70
Description:Ent-sandaracopimaradiene 3-hydroxylase.
Alternative Name: CYP701A.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.70
BRENDA Enzyme Link: BRENDA 1.14.14.70
KEGG Enzyme Link: KEGG1.14.14.70
BioCyc Enzyme Link: BioCyc 1.14.14.70
ExPASy Enzyme Link: ExPASy1.14.14.70
EC2PDB Enzyme Link: EC2PDB 1.14.14.70
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.70
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.70
IntEnz Enzyme Link: IntEnz 1.14.14.70
MEDLINE Enzyme Link: MEDLINE 1.14.14.70

EC number:1.14.14.70

MSA:

1.14.14.70;
Phylogenetic Tree:

1.14.14.70;
Uniprot:
M-CSA:
RHEA:41464 ent-sandaracopimara-8(14),15-diene + O2 + reduced [NADPH--hemoprotein reductase] = ent-sandaracopimaradien-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
RULE(radius=1) [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH2;+0:9]-[CH;+0:10]=[CH;+0:11]-1.[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:13].[*:4]-[n+;H0:5]1:[cH;+0:6]:[c;H0;+0:7](-[*:8]):[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:1.[OH2;+0:14]
Reaction
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References

TitleAuthorsDatePubMed ID
CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism.Wang Q, Hillwig ML, Wu Y, Peters RJ2012 Mar22247270
Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis.Wu Y, Wang Q, Hillwig ML, Peters RJ2013 Sep 123795884