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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor

ID:	1.14.14.71
Description:	Cucurbitadienol 11-hydroxylase.
Alternative Name:	CYP87D18.

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UniProtKB Enzyme Link:	UniProtKB 1.14.14.71
BRENDA Enzyme Link:	BRENDA 1.14.14.71
KEGG Enzyme Link:	KEGG1.14.14.71
BioCyc Enzyme Link:	BioCyc 1.14.14.71
ExPASy Enzyme Link:	ExPASy1.14.14.71
EC2PDB Enzyme Link:	EC2PDB 1.14.14.71
ExplorEnz Enzyme Link:	ExplorEnz 1.14.14.71
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.14.71
IntEnz Enzyme Link:	IntEnz 1.14.14.71
MEDLINE Enzyme Link:	MEDLINE 1.14.14.71

RHEA:55508	cucurbitadienol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 11-oxocucurbitadienol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]
RULE(radius=1)	[:1]-[CH2;+0:2]-[:3].[:4]-[N;H0;+0:5]1-[:6]:[:7]-[NH;+0:8]-[c;H0;+0:9](:[:10]):[c;H0;+0:11]-1:[nH;+0:12]:[:13].[:14]:[nH;+0:15]:[c;H0;+0:16]1:[c;H0;+0:17](:[:18])-[NH;+0:19]-[:20]:[:21]-[N;H0;+0:22]-1-[:23].[O;H0;+0:24]=[O;H0;+0:25].[O;H0;+0:26]=[O;H0;+0:27]>>[:1]-[C;H0;+0:2](-[:3])=[O;H0;+0:24].[:4]-[n;H0;+0:5]1:[:6]:[:7]:[n;H0;+0:8]:[c;H0;+0:9](:[:10])-[c;H0;+0:11]:1:[n;H0;+0:12]:[:13].[:14]:[n;H0;+0:15]:[c;H0;+0:16]1:[n;H0;+0:22](-[:23]):[:21]:[:20]:[n;H0;+0:19]:[c;H0;+0:17]-1:[:18].[OH2;+0:25].[OH2;+0:26].[OH2;+0:27]
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Title	Authors	Date	PubMed ID
Oxidation of Cucurbitadienol Catalyzed by CYP87D18 in the Biosynthesis of Mogrosides from Siraitia grosvenorii.	Zhang J, Dai L, Yang J, Liu C, Men Y, Zeng Y, Cai Y, Zhu Y, Sun Y	2016 May	26903528