EC number:1.14.14.76
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.76 |
|---|---|
| Description: | Ent-isokaurene C2/C3-hydroxylase. |
| Alternative Name: |
Ent-isokaurene C2-hydroxylase. CYP71Z6. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.76 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.76 |
| KEGG Enzyme Link: | KEGG1.14.14.76 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.76 |
| ExPASy Enzyme Link: | ExPASy1.14.14.76 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.76 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.76 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.76 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.76 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.76 |
EC number:1.14.14.76
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:56336 | ent-isokaurene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = ent-isokaurene-2beta,3beta-diol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[CH2;+0:3]-[*:4].[*:5]-[N;H0;+0:6]1-[*:7]:[*:8]-[NH;+0:9]-[c;H0;+0:10](:[*:11]):[c;H0;+0:12]-1:[nH;+0:13]:[*:14].[*:15]:[nH;+0:16]:[c;H0;+0:17]1:[c;H0;+0:18](:[*:19])-[NH;+0:20]-[*:21]:[*:22]-[N;H0;+0:23]-1-[*:24].[O;H0;+0:25]=[O;H0;+0:26].[O;H0;+0:27]=[O;H0;+0:28]>>[*:1]-[CH;+0:2](-[OH;+0:26])-[CH;+0:3](-[*:4])-[OH;+0:25].[*:5]-[n;H0;+0:6]1:[*:7]:[*:8]:[n;H0;+0:9]:[c;H0;+0:10](:[*:11])-[c;H0;+0:12]:1:[n;H0;+0:13]:[*:14].[*:15]:[n;H0;+0:16]:[c;H0;+0:17]1:[n;H0;+0:23](-[*:24]):[*:22]:[*:21]:[n;H0;+0:20]:[c;H0;+0:18]-1:[*:19].[OH2;+0:27].[OH2;+0:28] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis. | Kitaoka N, Wu Y, Xu M, Peters RJ | 2015 Sep | 25758958 |
| Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7. | Wu Y, Hillwig ML, Wang Q, Peters RJ | 2011 Nov 4 | 21985968 |