EC Tree |
1. Oxidoreductases |
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
ID: | 1.14.14.96 |
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Description: | 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase. |
Alternative Name: |
CYP98A3. 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase. |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 1.14.14.96 |
BRENDA Enzyme Link: | BRENDA 1.14.14.96 |
KEGG Enzyme Link: | KEGG1.14.14.96 |
BioCyc Enzyme Link: | BioCyc 1.14.14.96 |
ExPASy Enzyme Link: | ExPASy1.14.14.96 |
EC2PDB Enzyme Link: | EC2PDB 1.14.14.96 |
ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.96 |
PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.96 |
IntEnz Enzyme Link: | IntEnz 1.14.14.96 |
MEDLINE Enzyme Link: | MEDLINE 1.14.14.96 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:16265 | O2 + reduced [NADPH--hemoprotein reductase] + trans-5-O-(4-coumaroyl)-D-quinate = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + trans-5-O-caffeoyl-D-quinate |
RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures. | Kühnl T, Koch U, Heller W, Wellmann E | 1987 Oct | 2821918 |
Evolution of a novel phenolic pathway for pollen development. | Matsuno M, Compagnon V, Schoch GA, Schmitt M, Debayle D, Bassard JE, Pollet B, Hehn A, Heintz D, Ullmann P, Lapierre C, Bernier F, Ehlting J, Werck-Reichhart D | 2009 Sep 25 | 19779199 |
The Arabidopsis REF8 gene encodes the 3-hydroxylase of phenylpropanoid metabolism. | Franke R, Humphreys JM, Hemm MR, Denault JW, Ruegger MO, Cusumano JC, Chapple C | 2002 Apr | 11967091 |
CYP98A3 from Arabidopsis thaliana is a 3'-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway. | Schoch G, Goepfert S, Morant M, Hehn A, Meyer D, Ullmann P, Werck-Reichhart D | 2001 Sep 28 | 11429408 |