Enzyme

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EC Tree
     1. Oxidoreductases
        1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
            1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
ID:1.14.14.96
Description:5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase.
Alternative Name: CYP98A3.
5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.14.14.96
BRENDA Enzyme Link: BRENDA 1.14.14.96
KEGG Enzyme Link: KEGG1.14.14.96
BioCyc Enzyme Link: BioCyc 1.14.14.96
ExPASy Enzyme Link: ExPASy1.14.14.96
EC2PDB Enzyme Link: EC2PDB 1.14.14.96
ExplorEnz Enzyme Link: ExplorEnz 1.14.14.96
PRIAM enzyme-specific profiles Link: PRIAM 1.14.14.96
IntEnz Enzyme Link: IntEnz 1.14.14.96
MEDLINE Enzyme Link: MEDLINE 1.14.14.96
MSA:

1.14.14.96;

Phylogenetic Tree:

1.14.14.96;

Uniprot:
M-CSA:
RHEA:16265 O2 + reduced [NADPH--hemoprotein reductase] + trans-5-O-(4-coumaroyl)-D-quinate = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + trans-5-O-caffeoyl-D-quinate
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[*:9]:[cH;+0:10]:[*:11].[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[*:9]:[c;H0;+0:10](:[*:11])-[OH;+0:13].[OH2;+0:14]
Reaction
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References

TitleAuthorsDatePubMed ID
Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures.Kühnl T, Koch U, Heller W, Wellmann E1987 Oct2821918
Evolution of a novel phenolic pathway for pollen development.Matsuno M, Compagnon V, Schoch GA, Schmitt M, Debayle D, Bassard JE, Pollet B, Hehn A, Heintz D, Ullmann P, Lapierre C, Bernier F, Ehlting J, Werck-Reichhart D2009 Sep 2519779199
The Arabidopsis REF8 gene encodes the 3-hydroxylase of phenylpropanoid metabolism.Franke R, Humphreys JM, Hemm MR, Denault JW, Ruegger MO, Cusumano JC, Chapple C2002 Apr11967091
CYP98A3 from Arabidopsis thaliana is a 3'-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway.Schoch G, Goepfert S, Morant M, Hehn A, Meyer D, Ullmann P, Werck-Reichhart D2001 Sep 2811429408