EC number:1.14.14.99
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen |
| 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor |
| ID: | 1.14.14.99 | ||
|---|---|---|---|
| Description: | (S)-limonene 3-monooxygenase. | ||
| Alternative Name: |
CYP71D15. (-)-limonene 3-monooxygenase. (-)-limonene 3-hydroxylase. | ||
| Prosite: | PDOC00081; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.14.14.99 |
| BRENDA Enzyme Link: | BRENDA 1.14.14.99 |
| KEGG Enzyme Link: | KEGG1.14.14.99 |
| BioCyc Enzyme Link: | BioCyc 1.14.14.99 |
| ExPASy Enzyme Link: | ExPASy1.14.14.99 |
| EC2PDB Enzyme Link: | EC2PDB 1.14.14.99 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.14.14.99 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.14.14.99 |
| IntEnz Enzyme Link: | IntEnz 1.14.14.99 |
| MEDLINE Enzyme Link: | MEDLINE 1.14.14.99 |
EC number:1.14.14.99
| MSA: | |
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| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:15129 | (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (1S,6R)-isopiperitenol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[*:3].[*:4]-[N;H0;+0:5]1-[CH;+0:6]=[C;H0;+0:7](-[*:8])-[CH2;+0:9]-[CH;+0:10]=[CH;+0:11]-1.[H+;H0:12].[O;H0;+0:13]=[O;H0;+0:14]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:13].[*:4]-[n+;H0:5]1:[cH;+0:6]:[c;H0;+0:7](-[*:8]):[cH;+0:9]:[cH;+0:10]:[cH;+0:11]:1.[OH2;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Hydroxylation of limonene enantiomers and analogs by recombinant (-)-limonene 3- and 6-hydroxylases from mint (Mentha) species: evidence for catalysis within sterically constrained active sites. | Wüst M, Little DB, Schalk M, Croteau R | 2001 Mar 1 | 11368174 |
| Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)-4S-limonene-6-hydroxylase. | Lupien S, Karp F, Wildung M, Croteau R | 1999 Aug 1 | 10415126 |
| Monoterpene biosynthesis: specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perilla (Perilla frutescens) leaves. | Karp F, Mihaliak CA, Harris JL, Croteau R | 1990 Jan | 2297225 |