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1. Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor

ID:

1.14.15.1

Description:

Camphor 5-monooxygenase.

Alternative Name:

Cytochrome p450-cam.
Camphor 5-exo-methylene hydroxylase.

Prosite:

PDOC00081;

PDB:

PDB	Scop

Cath:

1.10.630.10; 3.30.390.30; 3.50.50.60;

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UniProtKB Enzyme Link:	UniProtKB 1.14.15.1
BRENDA Enzyme Link:	BRENDA 1.14.15.1
KEGG Enzyme Link:	KEGG1.14.15.1
BioCyc Enzyme Link:	BioCyc 1.14.15.1
ExPASy Enzyme Link:	ExPASy1.14.15.1
EC2PDB Enzyme Link:	EC2PDB 1.14.15.1
ExplorEnz Enzyme Link:	ExplorEnz 1.14.15.1
PRIAM enzyme-specific profiles Link:	PRIAM 1.14.15.1
IntEnz Enzyme Link:	IntEnz 1.14.15.1
MEDLINE Enzyme Link:	MEDLINE 1.14.15.1

RHEA:13525	(1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[putidaredoxin] = (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin]
RULE(radius=1)	[:1]-[CH2;+0:2]-[:3].[:4]-[Fe;H0;+0:5]-[:6].[:7]-[Fe;H0;+0:8]-[:9].[H+;H0:10].[H+;H0:11].[O;H0;+0:12]=[O;H0;+0:13]>>[:1]-[CH;+0:2](-[:3])-[OH;+0:12].[:4]-[Fe+;H0:5]-[:6].[:7]-[Fe+;H0:8]-[:9].[OH2;+0:13]
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Core-to-Core	More

Title	Authors	Date	PubMed ID
Mixed function oxidation. IV. An induced methylene hydroxylase in camphor oxidation.	Hedegaard J, Gunsalus IC	1965 Oct	4378858
The role of putidaredoxin and P450 cam in methylene hydroxylation.	Tyson CA, Lipscomb JD, Gunsalus IC	1972 Sep 25	4341491